Albahlal Abdullah, Khayyat Waleed, Alsulaiman Sulaiman M
King Khaled Eye Specialist Hospital, Riyadh, Kingdom of Saudi Arabia.
J Ophthalmic Inflamm Infect. 2023 May 25;13(1):28. doi: 10.1186/s12348-023-00340-7.
To report a case of combined central retinal vein occlusion (CRVO) with cilioretinal artery occlusion (CLRAO) that heralded the development of frosted branch angiitis (FBA).
A 25-year-old healthy male presented with sudden painless visual loss in his left eye with a visual acuity (VA) of 20/300. Fundus exam and fluorescein angiography showed signs of combined CRVO and CLRAO. Without treatment, his vision gradually improved until it reached 20/30 within four months. Five months after initial presentation, he returned with severe visual loss (20/400) in the same eye and a clinical picture of severe occlusive periphlebitis resembling a frosted branch angiitis pattern associated with severe macular edema. This was promptly and successfully treated with systemic steroids and immunosuppressive medications.
CRVO in young population can have an unusual course and one should carefully rule out underlying uveitic etiologies in each visit. Clinical suspicion and close follow‑up are required for early detection and timely management of FBA.
报告一例合并中央视网膜静脉阻塞（CRVO）和睫状视网膜动脉阻塞（CLRAO）并预示着霜样树枝状视网膜血管炎（FBA）发生的病例。
一名25岁健康男性因左眼突然无痛性视力丧失就诊，视力为20/300。眼底检查和荧光素血管造影显示合并CRVO和CLRAO的体征。未经治疗，其视力逐渐改善，直至四个月内达到20/30。初次就诊五个月后，他因同一眼严重视力丧失（20/400）复诊，临床表现为严重的闭塞性静脉周围炎，类似与严重黄斑水肿相关的霜样树枝状视网膜血管炎模式。经全身类固醇和免疫抑制药物迅速且成功地治疗。
年轻人群中的CRVO可能有不寻常的病程，每次就诊时都应仔细排除潜在的葡萄膜炎病因。对于FBA的早期检测和及时管理，需要临床怀疑和密切随访。
