University Hospital of Child and Adolescent Psychiatry and Psychotherapy, University of Bern.
Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, Faculty of Medicine, University of Cologne.
Personal Disord. 2023 Nov;14(6):625-635. doi: 10.1037/per0000630. Epub 2023 May 25.
Borderline personality disorder (BPD) has been associated with a reduced functional flexibility of the autonomic nervous system (ANS), indexed by decreased vagally mediated heart rate variability (vmHRV). Employing a comprehensive Section II-based assessment approach and a partial Section III-based assessment approach (including Criterion A of the alternative model of personality disorders [AMPD]), the present study investigates how different conceptualizations of personality disorders (PDs) according to the relate to ANS function. Using the BPD section of the Structured Clinical Interview for DSM-IV Axis II Disorders (SCID-II, a Section II-based assessment approach) and the Semistructured Interview for Personality Functioning DSM-5 (STiP-5.1, a Section III-based assessment approach), we conducted linear regression analyses to examine how categorical (BPD diagnosis) and dimensional (severity and domain) measures of PD are associated with ANS activity among adolescent psychiatric patients ( = 147, = 15.25 years). Replicating earlier findings, analyses revealed a statistically significant positive association between the SCID-II measures of BPD and heart rate (HR), = 0.43, (59) = 3.57, = .001, = .57, as well as a statistically significant negative association between the SCID-II measures of BPD and vmHRV, = -0.34, (59) = -2.74, = .008, = .47. Neither the STiP-5.1 total score nor the subscales of the Level of Personality Functioning Scale (LPFS) were associated with HR or vmHRV. The present findings indicate that the SCID-II may capture features of PD that are more informative of variance in physiological function than the STiP-5.1. (PsycInfo Database Record (c) 2023 APA, all rights reserved).
边缘型人格障碍 (BPD) 与自主神经系统 (ANS) 的功能灵活性降低有关，其表现为迷走神经介导的心率变异性 (vmHRV) 降低。本研究采用全面的基于第二部分的评估方法和基于第三部分的部分评估方法 (包括人格障碍替代模型的标准 A [AMPD])，探讨了不同的人格障碍 (PD) 概念与 ANS 功能的关系。使用 DSM-IV 轴 II 障碍的结构化临床访谈 (SCID-II，基于第二部分的评估方法) 和人格功能的半结构化访谈 DSM-5 (STiP-5.1，基于第三部分的评估方法) 的 BPD 部分，我们进行了线性回归分析，以检验 PD 的类别 (BPD 诊断) 和维度 (严重程度和领域) 测量如何与青少年精神科患者的 ANS 活动相关 (= 147, = 15.25 岁)。复制早期研究的发现，分析显示 SCID-II 对 BPD 的测量与心率 (HR) 呈显著正相关，= 0.43，(59)=3.57，=.001，=.57，以及 SCID-II 对 BPD 的测量与 vmHRV 呈显著负相关，= -0.34，(59)=-2.74，=.008，=.47。STiP-5.1 的总分和人格功能水平量表 (LPFS) 的分量表均与 HR 或 vmHRV 无关。本研究结果表明，SCID-II 可能比 STiP-5.1 更能捕捉 PD 的特征，这些特征对生理功能的变化更具信息性。(PsycInfo 数据库记录 (c) 2023 APA，保留所有权利)。
