Assal Hebatallah Hany, Hussein Sabah Ahmed, Mostafa Ahmed, El-Kareem Dalia Abd, Alfishawy Mostafa, Salah Maged, Mohammed Habiballah Galal
Department of Chest Medicine, Faculty of Medicine, Cairo University, Al Kasr Al Aini, Old Cairo, Cairo, Cairo Governorate 4240310, Egypt.
Cardiothoracic Surgery Department, Faculty of Medicine, Ain Shams University, Ramsis Street Square, El Weili, Cairo, Egypt.
IDCases. 2023 May 12;32:e01781. doi: 10.1016/j.idcr.2023.e01781. eCollection 2023.
Endobronchial mucormycosis is very rare with only few cases reported in the literature. Here, we report a rare presentation of pulmonary mucormycosis in a diabetic patient who presented with left lung collapse. Bronchoscopy revealed an endobronchial growth, mimicking a tumor, causing complete occlusion of the left main bronchus. Histopathology confirmed the diagnosis of invasive mucormycosis.
Male patient 35 years old with accidental discovered Diabetes Mellitus, complained of hoarseness of voice and dry irritating cough that didn't respond to antitussives and nonspecific treatment. CT chest was done and revealed left total lung collapse. Fiberoptic bronchoscopy was done and revealed total occlusion of the left main bronchus with whitish fungating glistening tissue from which biopsies were obtained. Histopathological examination was consistent with mucormycosis. A trial of medical treatment failed after which the patient was referred for surgical resection.
Successful treatment of mucormycosis requires early diagnosis; prompt administration of antifungal therapy, and surgical intervention when applicable. Aggressive surgical intervention to remove necrotic tissue is generally accepted as the therapeutic mainstay for endobronchial obstructing mucormycosis.
支气管内毛霉菌病非常罕见,文献中仅有少数病例报道。在此,我们报告一例糖尿病患者罕见的肺毛霉菌病表现,该患者出现左肺萎陷。支气管镜检查发现支气管内生长物,类似肿瘤,导致左主支气管完全阻塞。组织病理学确诊为侵袭性毛霉菌病。
一名35岁男性患者意外发现患有糖尿病,主诉声音嘶哑和干咳,使用止咳药和非特异性治疗无效。胸部CT检查显示左全肺萎陷。进行了纤维支气管镜检查,发现左主支气管完全阻塞,有白色、呈真菌样、有光泽的组织,从中获取了活检样本。组织病理学检查结果与毛霉菌病相符。药物治疗试验失败后,该患者被转诊进行手术切除。
成功治疗毛霉菌病需要早期诊断;及时给予抗真菌治疗,并在适当时进行手术干预。积极的手术干预以清除坏死组织通常被认为是支气管内阻塞性毛霉菌病的主要治疗方法。