Ng Khai Lip, Huan Nai-Chien, Nasaruddin Mona Zaria, Muhammad Noorul Afidza, Daut Ummi Nadira, Abdul Rahaman Jamalul Azizi
Department of Pulmonology Serdang Hospital Kajang Malaysia.
Department of Medicine Universiti Putra Malaysia Kajang Malaysia.
Respirol Case Rep. 2020 Dec 23;9(2):e00704. doi: 10.1002/rcr2.704. eCollection 2021 Feb.
Pulmonary mucormycosis is a rare but rapidly progressing and life-threatening fungal infection, usually affecting immunocompromised patients. We report a case of a previously healthy young lady who presented with prolonged cough, weight loss, and haemoptysis. Imaging showed left hilar mass with infiltration into the left main bronchus and concurrent mediastinal lymphadenopathy. Flexible bronchoscopy revealed an endobronchial mass occluding the left main bronchus. Tumour debulking was performed using rigid bronchoscopy with cryoprobe and snares. Histopathological examination revealed inflamed tissue with fungal organism. Fungal polymerase chain reaction (PCR) confirmed . She was treated with two weeks of intravenous amphotericin-B with complete clinical and radiological resolution.
肺毛霉病是一种罕见但进展迅速且危及生命的真菌感染，通常影响免疫功能低下的患者。我们报告一例既往健康的年轻女性病例，该患者出现长期咳嗽、体重减轻和咯血。影像学检查显示左肺门肿块，浸润至左主支气管，并伴有纵隔淋巴结肿大。纤维支气管镜检查发现一个阻塞左主支气管的支气管内肿块。使用硬支气管镜结合冷冻探头和圈套器进行肿瘤减容。组织病理学检查显示组织发炎并伴有真菌生物体。真菌聚合酶链反应（PCR）得以证实。她接受了两周的静脉注射两性霉素B治疗，临床和影像学均完全缓解。
