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中非加蓬中部法属维尔2017年至2019年疟疾临床病例数下降。

Decrease on malaria clinical cases from 2017 to 2019 in Franceville, Southeast Gabon, Central Africa.

作者信息

Boundenga Larson, Bignoumba Michelle, Dibakou Serge-Ely, Mombo Landry Erik, Moukagni-Mussadji Clauve Jauvert, Wora Dorothé Marielle, Kassa-Kassa Fabrice, Bisseye Cyrille, Onanga Richard

机构信息

International Centre of Medical Research of Franceville (CIRMF), Franceville, Gabon.

Department of Anthropology, University of Durham, UK.

出版信息

J Public Health Afr. 2023 May 4;14(3):1865. doi: 10.4081/jphia.2023.1865. eCollection 2023 Mar 31.

Abstract

BACKGROUND

In Gabon, malaria remains a major public health problem. All malaria cases with axillary temperature ≥ 37.5°C with a parasites density ≥ 1200/μL are serious cases and must be treated as a medical emergency. Thus, early diagnosis is essential for successful treatment. Because of the impact of malaria on the population, the surveillance of malaria infections in hospitals is urgently needed. The aim of this study was to to assess of clinical cases of malaria in a private health structure in Franceville between 2017 and 2019.

METHODS

For that, we conducted a retrospective study using data on malaria cases recorded in a private medical analysis laboratory in Franceville, southeast Gabon. Malaria was diagnosed in this laboratory using a Rapid Diagnostic Test and confirmed by microscopic analysis.

RESULTS

Analysis of 2518 patient forms revealed an increase in malaria prevalence in Franceville between 2017-2019. The global clinical cases was 26.1% (658/2015). Children under 5 years (44.0%) and patients aged 5-14 years (40.1%) were more affected than patients aged ≥15 years (18.8%, P=0.0001). Malaria infection was also significantly dependent on season and gender. We observed at least three Plasmodium species and the predominant Plasmodium species was 80.0%, followed by (19.5%) and (17.8%).

CONCLUSION

Our study showed that malaria remains a public health priority for the population of Franceville and that the prevalence of clinical cases of malaria at the laboratory decrease between 2017 and 2019. Our results highlight the need for strategies to control malaria in Franceville, adapted to epidemiological contexts and environmental constraint.

摘要

背景

在加蓬,疟疾仍然是一个主要的公共卫生问题。所有腋窝温度≥37.5°C且寄生虫密度≥1200/μL的疟疾病例均为严重病例,必须作为医疗紧急情况进行治疗。因此,早期诊断对于成功治疗至关重要。由于疟疾对人群的影响,迫切需要对医院中的疟疾感染进行监测。本研究的目的是评估2017年至2019年期间法国维尔一家私立卫生机构的疟疾病例情况。

方法

为此,我们进行了一项回顾性研究,使用了加蓬东南部法国维尔一家私立医学分析实验室记录的疟疾病例数据。该实验室使用快速诊断测试诊断疟疾,并通过显微镜分析进行确认。

结果

对2518份患者表格的分析显示,2017 - 2019年期间法国维尔的疟疾患病率有所上升。总体临床病例为26.1%(658/2015)。5岁以下儿童(44.0%)和5 - 14岁患者(40.1%)比15岁及以上患者(18.8%,P = 0.0001)受影响更大。疟疾感染也明显取决于季节和性别。我们观察到至少三种疟原虫物种,其中主要的疟原虫物种为80.0%,其次是(19.5%)和(17.8%)。

结论

我们的研究表明,疟疾仍然是法国维尔居民的公共卫生重点,并且该实验室2017年至2019年期间疟疾病例的患病率有所下降。我们的结果强调了在法国维尔制定适应流行病学背景和环境限制的疟疾控制策略的必要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d5eb/10204601/c9e5bed1c425/jpha-14-3-1865-g001.jpg

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