在英国生物库研究中，饮食模式的坚持与身体成分和肥胖测量的变化有关。

Dietary pattern adherence in association with changes in body composition and adiposity measurements in the UK Biobank study.

机构信息

Nuffield Department of Population Health, University of Oxford, Oxford, UK.

Nuffield Department of Population Health, University of Oxford, Oxford, UK; NIHR Oxford Biomedical Research Centre, University of Oxford, Oxford, UK.

出版信息

Obes Res Clin Pract. 2023 May-Jun;17(3):233-241. doi: 10.1016/j.orcp.2023.05.008. Epub 2023 May 24.

DOI:10.1016/j.orcp.2023.05.008

PMID:37230811

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10659985/

Abstract

BACKGROUND

Unhealthy dietary patterns (DP) have been frequently linked to avoidable ill-health, mediated in part through higher body mass index. However it is unclear how these patterns relate to specific components of body composition or fat distribution, and whether this may explain reported gender differences in the relationship between diet and health.

METHODS

Data from 101,046 UK Biobank participants with baseline bioimpedance analysis and anthropometric measures and dietary information on two or more occasions were used, of which 21,387 participants had repeated measures at follow up. Multivariable linear regressions estimated the associations between DP adherence (categorised in quintiles Q1-Q5) and body composition measures adjusted for a range of demographic and lifestyle confounders.

RESULTS

After 8.1 years of follow-up, individuals with high adherence (Q5) to the DP showed significantly positive changes in fat mass (mean, 95 % CI): 1.26 (1.12-1.39) kg in men, 1.11 (0.88-1.35) kg in women vs low adherence (Q1) - 0.09 (- 0.28 to 0.10) kg in men and - 0.26 (- 0.42 to - 0.11) kg in women; as well as in waist circumference (Q5): 0.93 (0.63-1.22) cm in men and 1.94 (1.63, 2.25) cm in women vs Q1 - 1.06 (- 1.34 to - 0.78) cm in men and 0.27 (- 0.02 to 0.57) cm in women.

CONCLUSION

Adherence to an unhealthy DP is positively associated with increased adiposity, especially in the abdominal region, which may help explain the observed associations with adverse health outcomes.

摘要

背景

不良的饮食模式（DP）与可避免的健康不良密切相关，部分原因是其导致的体重指数更高。然而，这些模式与身体成分或脂肪分布的具体组成部分之间的关系尚不清楚，并且这是否可以解释报告的饮食与健康之间的关系中的性别差异尚不清楚。

方法

使用来自 UK Biobank 的 101,046 名参与者的基线生物阻抗分析和人体测量学测量以及两次或多次饮食信息的数据，其中 21,387 名参与者在随访时有重复测量。多变量线性回归估计了 DP 依从性（五分位数 Q1-Q5 分类）与身体成分测量值之间的关联，这些关联在一系列人口统计学和生活方式混杂因素的调整后进行了评估。

结果

在 8.1 年的随访后，高 DP 依从性（Q5）的个体在脂肪量方面表现出明显的正向变化（均值，95%CI）：男性为 1.26（1.12-1.39）kg，女性为 1.11（0.88-1.35）kg，而低 DP 依从性（Q1）为 0.09（-0.28 至 0.10）kg，女性为-0.26（-0.42 至 -0.11）kg；腰围方面也表现出正向变化（Q5）：男性为 0.93（0.63-1.22）cm，女性为 1.94（1.63, 2.25）cm，而 Q1 为-1.06（-1.34 至 -0.78）cm，女性为 0.27（-0.02 至 0.57）cm。