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米粉和葡萄糖补液溶液作为婴儿急性脱水腹泻口服疗法的对照试验。

Controlled trial of rice powder and glucose rehydration solutions as oral therapy for acute dehydrating diarrhea in infants.

作者信息

Mohan M, Sethi J S, Daral T S, Sharma M, Bhargava S K, Sachdev H P

出版信息

J Pediatr Gastroenterol Nutr. 1986 May-Jun;5(3):423-7. doi: 10.1097/00005176-198605000-00015.

DOI:10.1097/00005176-198605000-00015
PMID:3723262
Abstract

A controlled, randomized trial was conducted in 50 infants (3 to 18 months old) hospitalized with acute noncholera dehydrating diarrhea to compare the safety, efficacy, and acceptability of the standard World Health Organization (WHO) recommended glucose oral rehydration solution (ORS) (Group A: 25 infants) with that of a rice powder ORS (Group B: 25 infants), containing 30 g/L of rice powder instead of glucose (20 g/L). The electrolyte composition of both solutions was identical. The proportion of successfully treated patients in each group was 92%, and the two rehydrating solutions proved comparable in correcting and maintaining the hydration status and the serum sodium and potassium levels. The mean rehydration time, stool output, stool frequency, ORS intake, weight gain, and urine output were comparable (p greater than 0.05) in both groups. It is concluded that rice powder ORS is safe, effective, and acceptable as the standard WHO glucose ORS for the treatment of acute noncholera dehydrating diarrhea in infants.

摘要

对50例因急性非霍乱性脱水腹泻住院的婴儿(3至18个月大)进行了一项对照随机试验,以比较标准世界卫生组织(WHO)推荐的葡萄糖口服补液盐(ORS)(A组:25例婴儿)与米粉ORS(B组:25例婴儿)的安全性、有效性和可接受性,后者含有30 g/L米粉而非葡萄糖(20 g/L)。两种溶液的电解质组成相同。每组成功治疗的患者比例均为92%,两种补液溶液在纠正和维持水合状态以及血清钠和钾水平方面具有可比性。两组的平均补液时间、粪便排出量、排便频率、ORS摄入量、体重增加和尿量均具有可比性(p大于0.05)。得出结论,对于治疗婴儿急性非霍乱性脱水腹泻,米粉ORS作为WHO标准葡萄糖ORS是安全、有效且可接受的。

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Controlled trial of rice powder and glucose rehydration solutions as oral therapy for acute dehydrating diarrhea in infants.米粉和葡萄糖补液溶液作为婴儿急性脱水腹泻口服疗法的对照试验。
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引用本文的文献

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The effect of oral rehydration solution and recommended home fluids on diarrhoea mortality.口服补液盐和推荐的家庭补液对腹泻死亡率的影响。
Int J Epidemiol. 2010 Apr;39 Suppl 1(Suppl 1):i75-87. doi: 10.1093/ije/dyq025.
2
Is rice based oral rehydration therapy effective in young infants?以大米为基础的口服补液疗法对小婴儿有效吗?
Arch Dis Child. 1994 Jul;71(1):19-23. doi: 10.1136/adc.71.1.19.
3
Impact of rice based oral rehydration solution on stool output and duration of diarrhoea: meta-analysis of 13 clinical trials.基于大米的口服补液溶液对粪便排出量和腹泻持续时间的影响:13项临床试验的荟萃分析
BMJ. 1992 Feb 1;304(6822):287-91. doi: 10.1136/bmj.304.6822.287.