el-Mougi M, Hegazi E, Galal O, el Akkad N, el-Abhar A, Nour N, el-Hadi Emam M, Ahmadi A R
Diarrhoeal Disease Research and Rehydration Centre (DDRRC), Bab El Shar'reya University Hospital, Cairo, Egypt.
J Pediatr Gastroenterol Nutr. 1988 Jul-Aug;7(4):572-6. doi: 10.1097/00005176-198807000-00016.
We report a controlled clinical trial of rice powder-based oral rehydration solution (ORS) versus glucose ORS on the outcome of acute diarrhea in infants. The rice ORS group (n = 30) received ORS containing 50 g rice powder instead of standard WHO solution (20 g glucose, n = 30). Formula-fed male infants were enrolled to enable calculation of milk intake and excretion of urine. Patient allocation to either group depended on the method of random permuted blocks. Both groups were comparable regarding age (4-18 months), duration of diarrhea, number of bowel movements or vomiting per 24 h, rectal temperature, dehydration score, and nutritional status. Results revealed that the rice ORS group had a shorter duration of diarrhea (28.4 +/- 5.1 vs 34.3 +/- 2.3 h) and greater mean weight gain in the first 24 h as percentage of recovery weight (5.7 +/- 0.5% vs 4.1 +/- 0.6%). Furthermore, the mean amount of ORS intake, mean stool output, and mean number of episodes of vomiting were lower in the rice-ORS group as compared with the glucose ORS group. All differences were statistically significant. Due to its observed superiority and low cost, the widespread use of rice ORS should be considered for treatment of acute diarrhea.
我们报告了一项关于基于米粉的口服补液盐（ORS）与葡萄糖ORS对婴儿急性腹泻治疗效果的对照临床试验。米粉ORS组（n = 30）接受含有50 g米粉的ORS，而非标准的世界卫生组织溶液（20 g葡萄糖，n = 30）。纳入配方奶喂养的男婴以便计算奶摄入量和尿量。患者分配至两组中的哪一组取决于随机排列区组法。两组在年龄（4 - 18个月）、腹泻持续时间、每24小时排便次数或呕吐次数、直肠温度、脱水评分及营养状况方面具有可比性。结果显示，米粉ORS组腹泻持续时间较短（28.4 +/- 5.1 vs 34.3 +/- 2.3小时），且在最初24小时内以恢复体重百分比计算的平均体重增加更多（5.7 +/- 0.5% vs 4.1 +/- 0.6%）。此外，与葡萄糖ORS组相比，米粉ORS组的ORS平均摄入量、平均粪便排出量及平均呕吐发作次数更低。所有差异均具有统计学意义。鉴于其观察到的优势及低成本，应考虑广泛使用米粉ORS来治疗急性腹泻。
