Göksu N
J Pediatr Gastroenterol Nutr. 1986 May-Jun;5(3):459-62. doi: 10.1097/00005176-198605000-00022.
Serum and hepatic zinc (Zn), copper (Cu), and magnesium (Mg) contents were determined in 21 children with morphologically proven liver cirrhosis: 11 with cryptogenic cirrhosis (CC) and 10 with secondary biliary cirrhosis (SBC). These determinations were also carried out in eight patients with idiopathic portal hypertension. Serum levels of Zn, Cu, and Mg in 23 healthy children and hepatic contents of these minerals in 22 patients without liver pathology were evaluated. All determinations were carried out by atomic absorption spectrophotometry by using special tubes, needles, and syringes in appropriate conditions. Tissue Zn and Mg contents were decreased, but the Cu level was elevated significantly in childhood cirrhosis; in almost all patients with SBC and half of the CC cases. Serum levels of these minerals generally did not correlate to tissue levels in childhood cirrhosis.
对21例经形态学证实为肝硬化的儿童测定了血清及肝脏中的锌（Zn）、铜（Cu）和镁（Mg）含量：11例为隐源性肝硬化（CC），10例为继发性胆汁性肝硬化（SBC）。对8例特发性门静脉高压患者也进行了这些测定。评估了23名健康儿童的血清Zn、Cu和Mg水平以及22例无肝脏病变患者的这些矿物质的肝脏含量。所有测定均在适当条件下使用特殊试管、针头和注射器通过原子吸收分光光度法进行。儿童肝硬化时组织Zn和Mg含量降低，但Cu水平显著升高；几乎所有SBC患者和半数CC患者均如此。儿童肝硬化时这些矿物质的血清水平通常与组织水平无关。
