基于 TiC/TiO 异质结构的无识别分子光电化学传感器用于多巴胺监测。
A Recognition-Molecule-Free Photoelectrochemical Sensor Based on TiC/TiO Heterostructure for Monitoring of Dopamine.
机构信息
School of Economics and Statistics c/o Center for Advanced Analytical Science, c/o School of Chemistry and Chemical Engineering, Guangzhou Key Laboratory of Sensing Materials and Devices, Guangdong Engineering Technology Research Center for Photoelectric Sensing Materials and Devices, Guangzhou University, Guangzhou 510006, China.
Guangdong Provincial Key Laboratory of Psychoactive Substances Monitoring and Safety, Anti-Drug Tethnology Center of Guangdong Province, Guangzhou 510230, China.
出版信息
Biosensors (Basel). 2023 May 7;13(5):526. doi: 10.3390/bios13050526.
Herein, a novel, recognition-molecule-free electrode based on TiC/TiO composites was synthesized using TiC as the Ti source and TiO in situ formed by oxidation on the TiC surface for the selective detection of dopamine (DA). The TiO in situ formed by oxidation on the TiC surface not only increased the catalytically active surface for DA binding but also accelerated the carrier transfer due to the coupling between TiO and TiC, resulting in a better photoelectric response than pure TiO. Through a series of experimental conditions optimization, the photocurrent signals obtained by the MT100 electrode were proportional to the DA concentration from 0.125 to 400 µM, with a detection limit estimated at 0.045 µM. We also monitored DA in human blood serum samples using the MT100 electrode. The results showed good recovery, demonstrating the promising use of the sensor for the analysis of DA in real samples.
本文报道了一种新型的无识别分子电极，该电极以 TiC 作为 Ti 源，通过 TiC 表面的氧化原位生成 TiO，用于多巴胺（DA）的选择性检测。TiC 表面氧化原位生成的 TiO 不仅增加了与 DA 结合的催化活性表面，而且由于 TiO 和 TiC 之间的耦合加速了载流子转移，从而产生了比纯 TiO 更好的光电响应。通过一系列实验条件的优化，MT100 电极获得的光电流信号与 0.125 至 400µM 的 DA 浓度呈正比，检测限估计为 0.045µM。我们还使用 MT100 电极监测了人血清样品中的 DA。结果表明回收率良好，表明该传感器在实际样品中分析 DA 具有广阔的应用前景。
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