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切卡病毒与斑块状副银屑病显著相关:皮肤拭子和活检样本中均有高患病率。

Significant Association of Cutavirus With Parapsoriasis en Plaques: High Prevalence Both in Skin Swab and Biopsy Samples.

机构信息

Department of Virology, University of Helsinki, Helsinki, Finland.

Pediatric Research Center, Children's Hospital, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.

出版信息

Clin Infect Dis. 2023 Oct 5;77(7):987-990. doi: 10.1093/cid/ciad320.

DOI:10.1093/cid/ciad320
PMID:37234048
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10552579/
Abstract

Cutavirus (CuV) is associated with cutaneous T-cell lymphoma (CTCL), of which parapsoriasis is a precursor. Our study reveals a significantly higher CuV-DNA prevalence in skin swabs of parapsoriasis patients (6/13; 46.2%) versus those of healthy adults (1/51; 1.96%). Eight patients (8/12; 66.7%) had CuV DNA in biopsied skin, and 4 developed CTCL.

摘要

切瘤病毒(CuV)与皮肤 T 细胞淋巴瘤(CTCL)相关,而副银屑病是其前体疾病。我们的研究显示,副银屑病患者的皮肤拭子中 CuV-DNA 的阳性率明显更高(6/13;46.2%),而健康成年人的阳性率为 1/51(1.96%)。12 名患者中有 8 名(8/12;66.7%)在活检皮肤中存在 CuV DNA,4 名患者发展为 CTCL。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4967/10552579/bcd62c3bfd44/ciad320f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4967/10552579/bcd62c3bfd44/ciad320f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4967/10552579/bcd62c3bfd44/ciad320f1.jpg

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