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用于生物医学应用的液晶材料。

Liquid Crystal Materials for Biomedical Applications.

机构信息

Shanghai Xuhui Central Hospital, Zhongshan-Xuhui Hospital, and the Shanghai Key Laboratory of Medical Epigenetics, the International Co-laboratory of Medical Epigenetics and Metabolism (Ministry of Science and Technology), Institutes of Biomedical Sciences, Fudan University, Shanghai, 200032, China.

Department of Rheumatology and Immunology, Nanjing Drum Tower Hospital, School of Biological Science and Medical Engineering Southeast University, Nanjing, 210096, China.

出版信息

Adv Mater. 2023 Sep;35(36):e2300220. doi: 10.1002/adma.202300220. Epub 2023 Jul 12.

Abstract

Liquid crystal is a state of matter being intermediate between solid and liquid. Liquid crystal materials exhibit both orientational order and fluidity. While liquid crystals have long been highly recognized in the display industry, in recent decades, liquid crystals provide new opportunities into the cross-field of material science and biomedicine due to their biocompatibility, multifunctionality, and responsiveness. In this review, the latest achievements of liquid crystal materials applied in biomedical fields are summarized. The start is made by introducing the basic concepts of liquid crystals, and then shifting to the components of liquid crystals as well as functional materials derived therefrom. After that, the ongoing and foreseeable applications of liquid crystal materials in the biomedical field with emphasis put on several cutting-edge aspects, including drug delivery, bioimaging, tissue engineering, implantable devices, biosensing, and wearable devices are discussed. It is hoped that this review will stimulate ingenious ideas for the future generation of liquid crystal-based drug development, artificial implants, disease diagnosis, health status monitoring, and beyond.

摘要

液晶是介于固态和液态之间的一种物质状态。液晶材料表现出取向有序和流动性。虽然液晶在显示行业早已得到高度认可,但在最近几十年,由于其生物相容性、多功能性和响应性,液晶为材料科学和生物医学的交叉领域提供了新的机会。在这篇综述中,总结了液晶材料在生物医学领域的最新应用成果。首先介绍了液晶的基本概念,然后转向液晶的组成部分以及由此衍生的功能材料。之后,重点讨论了液晶材料在药物输送、生物成像、组织工程、可植入设备、生物传感和可穿戴设备等几个前沿领域的当前和可预见的应用。希望这篇综述能为下一代基于液晶的药物开发、人工植入物、疾病诊断、健康状况监测等领域激发创意。

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