National Centre for Sport and Exercise Medicine, School of Sport, Exercise and Health Sciences, Loughborough University, UK; College of Sport Sciences, Jeddah University, Saudi Arabia; National Institute for Health and Care Research (NIHR) Leicester Biomedical Research Centre, University Hospitals of Leicester NHS Trust and University of Leicester, UK.
National Centre for Sport and Exercise Medicine, School of Sport, Exercise and Health Sciences, Loughborough University, UK; National Institute for Health and Care Research (NIHR) Leicester Biomedical Research Centre, University Hospitals of Leicester NHS Trust and University of Leicester, UK.
Neurosci Biobehav Rev. 2023 Sep;152:105247. doi: 10.1016/j.neubiorev.2023.105247. Epub 2023 May 25.
This systematic review examined whether neural responses to visual food-cues measured by functional magnetic resonance imaging (fMRI) are influenced by physical activity. Seven databases were searched up to February 2023 for human studies evaluating visual food-cue reactivity using fMRI alongside an assessment of habitual physical activity or structured exercise exposure. Eight studies (1 exercise training, 4 acute crossover, 3 cross-sectional) were included in a qualitative synthesis. Structured acute and chronic exercise appear to lower food-cue reactivity in several brain regions, including the insula, hippocampus, orbitofrontal cortex (OFC), postcentral gyrus and putamen, particularly when viewing high-energy-density food cues. Exercise, at least acutely, may enhance appeal of low-energy-density food-cues. Cross-sectional studies show higher self-reported physical activity is associated with lower reactivity to food-cues particularly of high-energy-density in the insula, OFC, postcentral gyrus and precuneus. This review shows that physical activity may influence brain food-cue reactivity in motivational, emotional, and reward-related processing regions, possibly indicative of a hedonic appetite-suppressing effect. Conclusions should be drawn cautiously given considerable methodological variability exists across limited evidence.
本系统评价研究了功能磁共振成像 (fMRI) 测量的视觉食物线索的神经反应是否受到身体活动的影响。截至 2023 年 2 月，我们在七个数据库中搜索了人类研究，这些研究使用 fMRI 评估了视觉食物线索反应性，并评估了习惯性身体活动或结构化运动暴露情况。八项研究（1 项运动训练，4 项急性交叉，3 项横断面）被纳入定性综合分析。有组织的急性和慢性运动似乎会降低大脑中多个区域的食物线索反应性，包括岛叶、海马体、眶额皮质（OFC）、中央后回和壳核，尤其是在观看高能量密度食物线索时。至少在急性运动时，运动可能会增强对低能量密度食物线索的吸引力。横断面研究表明，较高的自我报告身体活动与对食物线索的反应性较低有关，尤其是在岛叶、OFC、中央后回和楔前叶的高能量密度食物线索。本综述表明，身体活动可能会影响与动机、情绪和奖励相关的大脑食物线索反应性，这可能表明存在愉悦食欲抑制效应。鉴于有限的证据存在相当大的方法学变异性，应谨慎得出结论。
