Sunderam G, McDonald R J, Maniatis T, Oleske J, Kapila R, Reichman L B
JAMA. 1986 Jul 18;256(3):362-6.
Tuberculosis has not been well documented as a complication of the acquired immunodeficiency syndrome (AIDS). We studied 48 cases of mycobacterial diseases among a group of 136 adult patients with AIDS over a 43-month period. Twenty-nine of them had severe and unusual manifestations of disease due to Mycobacterium tuberculosis, predominantly extrapulmonary and disseminated. Tuberculosis was more common among Haitians (4/8) and intravenous drug abusers (24/102) than among homosexuals who did not abuse drugs (0/22). Twelve of 21 patients with tuberculosis who were treated responded well, whereas three developed progressive disease indicative of treatment failure. Severe and unusual presentation of overwhelming tuberculosis in appropriate clinical circumstances may be considered an infection predictive of the presence of AIDS.
结核病作为获得性免疫缺陷综合征（艾滋病）的一种并发症，相关记录并不完善。在43个月的时间里，我们对一组136名成年艾滋病患者中的48例分枝杆菌病病例进行了研究。其中29例因结核分枝杆菌感染而出现严重且不寻常的疾病表现，主要为肺外和播散性病变。结核病在海地人（4/8）和静脉吸毒者（24/102）中比在不吸毒的同性恋者（0/22）中更为常见。21例接受治疗的结核病患者中有12例反应良好，而3例病情进展，提示治疗失败。在适当的临床情况下，严重且不寻常的播散性结核病表现可被视为预测艾滋病存在的一种感染。
