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豚鼠人工耳蜗植入术后残余听力的有限元建模

Finite Element Modeling of Residual Hearing after Cochlear Implant Surgery in Chinchillas.

作者信息

Castle Nicholas, Liang Junfeng, Smith Matthew, Petersen Brett, Matson Cayman, Eldridge Tara, Zhang Ke, Lee Chung-Hao, Liu Yingtao, Dai Chenkai

机构信息

Department of Aerospace and Mechanical Engineering, University of Oklahoma, Norman, OK 73019, USA.

出版信息

Bioengineering (Basel). 2023 Apr 27;10(5):539. doi: 10.3390/bioengineering10050539.

Abstract

Cochlear implant (CI) surgery is one of the most utilized treatments for severe hearing loss. However, the effects of a successful scala tympani insertion on the mechanics of hearing are not yet fully understood. This paper presents a finite element (FE) model of the chinchilla inner ear for studying the interrelationship between the mechanical function and the insertion angle of a CI electrode. This FE model includes a three-chambered cochlea and full vestibular system, accomplished using µ-MRI and µ-CT scanning technologies. This model's first application found minimal loss of residual hearing due to insertion angle after CI surgery, and this indicates that it is a reliable and helpful tool for future applications in CI design, surgical planning, and stimuli setup.

摘要

人工耳蜗植入(CI)手术是重度听力损失最常用的治疗方法之一。然而,成功的鼓阶插入对听力机制的影响尚未完全了解。本文提出了一种用于研究CI电极机械功能与插入角度之间相互关系的灰鼠内耳有限元(FE)模型。该FE模型包括一个三室耳蜗和完整的前庭系统,通过µ-MRI和µ-CT扫描技术构建。该模型的首次应用发现CI手术后因插入角度导致的残余听力损失极小,这表明它是未来在CI设计、手术规划和刺激设置中应用的可靠且有用的工具。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/de8e/10215081/622ec6291e05/bioengineering-10-00539-g001.jpg

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