外科医生使用预防性抗生素的“困扰”
The "Torment" of Surgical Antibiotic Prophylaxis among Surgeons.
作者信息
Sartelli Massimo, Coccolini Federico, Carrieri Angeloantonio, Labricciosa Francesco M, Cicuttin Enrico, Catena Fausto
机构信息
Department of Surgery, Macerata Hospital, 62100 Macerata, Italy.
Department of General, Emergency and Trauma Surgery, Pisa University Hospital, 56100 Pisa, Italy.
出版信息
Antibiotics (Basel). 2021 Nov 6;10(11):1357. doi: 10.3390/antibiotics10111357.
Abstract
Surgical antibiotic prophylaxis (SAP) is one of the peri-operative measures for preventing surgical site infections (SSIs). Its goal is to counteract the proliferation of bacteria in the surgical site during intervention in order to reduce the risk of SSIs. SAP should be administered for surgical interventions where the benefit expected (prevention of SSIs) is higher compared to the risk (serious side effects, such as acute kidney injury, infection, and the spread of antimicrobial resistance). In prescribing SAP, surgeons should have both the awareness necessary "to handle antibiotics with care", and the knowledge required to use them appropriately.
摘要
外科手术预防性抗生素应用（SAP）是预防手术部位感染（SSIs）的围手术期措施之一。其目的是在手术干预期间对抗手术部位细菌的增殖，以降低手术部位感染的风险。对于预期益处（预防手术部位感染）高于风险（严重副作用，如急性肾损伤、感染和抗菌药物耐药性传播）的外科手术干预，应使用外科手术预防性抗生素。在开具外科手术预防性抗生素处方时，外科医生应具备 “谨慎使用抗生素” 所需的意识，以及正确使用抗生素所需的知识。
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