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评估卵巢癌患者选定免疫和分子参数测定的潜在诊断效用。

Evaluation of the Potential Diagnostic Utility of the Determination of Selected Immunological and Molecular Parameters in Patients with Ovarian Cancer.

作者信息

Englisz Aleksandra, Smycz-Kubańska Marta, Mielczarek-Palacz Aleksandra

机构信息

The Doctoral School, Medical University of Silesia, 40-055 Katowice, Poland.

Department of Immunology and Serology, Faculty of Pharmaceutical Sciences in Sosnowiec, Medical University of Silesia, 40-055 Katowice, Poland.

出版信息

Diagnostics (Basel). 2023 May 12;13(10):1714. doi: 10.3390/diagnostics13101714.

Abstract

Ovarian cancer is one of the most serious challenges in modern gynaecological oncology. Due to its non-specific symptoms and the lack of an effective screening procedure to detect the disease at an early stage, ovarian cancer is still marked by a high mortality rate among women. For this reason, a great deal of research is being carried out to find new markers that can be used in the detection of ovarian cancer to improve early diagnosis and survival rates of women with ovarian cancer. Our study focuses on presenting the currently used diagnostic markers and the latest selected immunological and molecular parameters being currently investigated for their potential use in the development of new diagnostic and therapeutic strategies.

摘要

卵巢癌是现代妇科肿瘤学中最严峻的挑战之一。由于其症状不具特异性,且缺乏在疾病早期进行检测的有效筛查程序,卵巢癌在女性中的死亡率仍然很高。因此,人们正在进行大量研究,以寻找可用于卵巢癌检测的新标志物,从而提高卵巢癌女性患者的早期诊断率和生存率。我们的研究重点是介绍目前使用的诊断标志物以及最新选定的免疫和分子参数,这些参数目前正在研究中,以探讨其在开发新的诊断和治疗策略方面的潜在用途。

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本文引用的文献

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Recent advances of non-coding RNAs in ovarian cancer prognosis and therapeutics.非编码RNA在卵巢癌预后和治疗中的最新进展
Ther Adv Med Oncol. 2022 Aug 12;14:17588359221118010. doi: 10.1177/17588359221118010. eCollection 2022.

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