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吸气肌训练负荷对晚期肺癌伴呼吸困难患者的影响及效用

Effects and Usefulness of Inspiratory Muscle Training Load in Patients with Advanced Lung Cancer with Dyspnea.

作者信息

Sakai Yasunari, Yamaga Takayoshi, Yamamoto Shuhei, Matsumori Keiji, Ichiyama Takashi, Hanaoka Masayuki, Ikegami Shota, Horiuchi Hiroshi

机构信息

Department of Rehabilitation, Shinshu University Hospital, Matsumoto 390-8621, Japan.

Department of Occupational Therapy, Faculty of Medical Science, Nagoya Women's University, Nagoya 467-8610, Japan.

出版信息

J Clin Med. 2023 May 10;12(10):3396. doi: 10.3390/jcm12103396.

Abstract

BACKGROUND

Patients with advanced lung cancer tend to experience dyspnea. Pulmonary rehabilitation has been reported as a method for relieving dyspnea. However, exercise therapy imposes a high burden on patients, and it is difficult to sustain in many cases. Inspiratory muscle training (IMT) imposes a relatively low burden on patients with advanced lung cancer; however, its benefits have not been demonstrated.

METHODS

We retrospectively analyzed 71 patients who were hospitalized for medical treatment. The participants were divided into an exercise therapy group and an IMT load + exercise therapy group. Changes in maximal inspiratory pressure (MIP) and dyspnea were examined using a two-way repeated measures analysis of variance.

RESULTS

MIP variations significantly increase in the IMT load group, with significant differences between baseline and week 1, between week 1 and week 2, and between baseline and week 2. The analysis also showed that the variations in dyspnea decreased in the IMT load + exercise therapy group with significant differences between baseline and week 1 and between baseline and week 2.

CONCLUSIONS

The results show that IMT is useful and has a high persistence rate in patients with advanced lung cancer who present dyspnea and cannot perform high-intensity exercise therapy.

摘要

背景

晚期肺癌患者往往会出现呼吸困难。据报道,肺康复是缓解呼吸困难的一种方法。然而,运动疗法给患者带来了沉重负担,在许多情况下难以持续。吸气肌训练(IMT)对晚期肺癌患者的负担相对较低;然而,其益处尚未得到证实。

方法

我们回顾性分析了71名因治疗而住院的患者。参与者被分为运动治疗组和IMT负荷+运动治疗组。使用双向重复测量方差分析来检查最大吸气压力(MIP)和呼吸困难的变化。

结果

IMT负荷组的MIP变化显著增加,在基线与第1周之间、第1周与第2周之间以及基线与第2周之间存在显著差异。分析还表明,IMT负荷+运动治疗组的呼吸困难变化有所减少,在基线与第1周之间以及基线与第2周之间存在显著差异。

结论

结果表明,IMT对出现呼吸困难且无法进行高强度运动疗法的晚期肺癌患者有用且具有较高的持续率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9003/10219417/4c653e3a9608/jcm-12-03396-g001.jpg

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