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成人嗜酸性粒细胞性食管炎患者的饮食策略:最新综述。

Dietary Strategies in Adult Patients with Eosinophilic Esophagitis: A State-of-the-Art Review.

机构信息

Department of Internal Medicine and Therapeutics, University of Pavia, 27100 Pavia, Italy.

First Department of Internal Medicine, Fondazione IRCCS San Matteo, 27100 Pavia, Italy.

出版信息

Nutrients. 2023 May 22;15(10):2409. doi: 10.3390/nu15102409.

DOI:10.3390/nu15102409
PMID:37242291
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10223610/
Abstract

Allergen-free diets are a specific and effective anti-inflammatory therapy for eosinophilic esophagitis. They should be carried out by a multidisciplinary team to reduce side effects and improve adherence. According to recent guidelines and expert opinions, empirical diets with a reduced number of eliminated food categories and a step-up approach are the most encouraged strategy to reduce the number of endoscopies to identify food trigger(s) and maximize clinical results and adherence. Despite the fact that allergy testing-based diets are not recommended at a population level, geographical sensitization patterns may play a role in some patients in specific areas, such as in Southern and Central Europe.

摘要

无过敏原饮食是嗜酸性粒细胞性食管炎的一种特定且有效的抗炎治疗方法。应由多学科团队进行实施,以减少副作用并提高患者的依从性。根据最近的指南和专家意见,减少消除食物种类的经验性饮食和逐步升级的方法是最受鼓励的策略,可以减少识别食物触发物所需的内镜检查次数,最大限度地提高临床效果和患者的依从性。尽管基于过敏测试的饮食在人群层面上不被推荐,但在某些特定地区(如南欧和中欧),地理致敏模式可能在某些患者中起作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f18e/10223610/3592a6f348a0/nutrients-15-02409-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f18e/10223610/f7da429a9033/nutrients-15-02409-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f18e/10223610/55bec701d5f9/nutrients-15-02409-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f18e/10223610/3592a6f348a0/nutrients-15-02409-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f18e/10223610/f7da429a9033/nutrients-15-02409-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f18e/10223610/55bec701d5f9/nutrients-15-02409-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f18e/10223610/3592a6f348a0/nutrients-15-02409-g003.jpg

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本文引用的文献

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Allergy-Test-Based Elimination Diets for the Treatment of Eosinophilic Esophagitis: A Systematic Review of Their Efficacy.基于过敏测试的排除饮食疗法治疗嗜酸性粒细胞性食管炎:疗效的系统评价
J Clin Med. 2022 Sep 24;11(19):5631. doi: 10.3390/jcm11195631.
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Eosinophilic oesophagitis in Denmark: Population-based incidence and prevalence in a nationwide study from 2008 to 2018.丹麦嗜酸细胞性食管炎:2008 年至 2018 年全国性研究中的基于人群的发病率和患病率。
United European Gastroenterol J. 2022 Sep;10(7):640-650. doi: 10.1002/ueg2.12273. Epub 2022 Sep 15.
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High prevalence of sensitization to non-specific lipid transfer protein in adult patients with primary eosinophilic gastrointestinal disorders in Italy: a single center series.
新西兰嗜酸性粒细胞性食管炎成人的生活质量因素。
Nutrients. 2024 Oct 10;16(20):3437. doi: 10.3390/nu16203437.
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Food Allergy: Epidemiology, Pathogenesis, Diagnosis, and Treatment.食物过敏:流行病学、发病机制、诊断与治疗
J Clin Med. 2024 Oct 9;13(19):6010. doi: 10.3390/jcm13196010.
意大利原发性嗜酸性胃肠道疾病成年患者对非特异性脂质转移蛋白致敏的高患病率:一项单中心研究系列
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Primary eosinophilic gastrointestinal disorders and allergy: Clinical and therapeutic implications.原发性嗜酸性胃肠道疾病与过敏:临床及治疗意义
Clin Transl Allergy. 2022 May 23;12(5):e12146. doi: 10.1002/clt2.12146. eCollection 2022 May.
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British Society of Gastroenterology (BSG) and British Society of Paediatric Gastroenterology, Hepatology and Nutrition (BSPGHAN) joint consensus guidelines on the diagnosis and management of eosinophilic oesophagitis in children and adults.英国胃肠病学会(BSG)和英国儿科胃肠病学、肝病学和营养学学会(BSPGHAN)联合制定的儿童和成人嗜酸性食管炎的诊断和管理共识指南。
Gut. 2022 Aug;71(8):1459-1487. doi: 10.1136/gutjnl-2022-327326. Epub 2022 May 23.
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Disease Burden and Unmet Need in Eosinophilic Esophagitis.嗜酸性粒细胞性食管炎的疾病负担和未满足的需求。
Am J Gastroenterol. 2022 Aug 1;117(8):1231-1241. doi: 10.14309/ajg.0000000000001777. Epub 2022 Apr 13.
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The need for a reliable non-invasive diagnostic biomarker for eosinophilic oesophagitis.对嗜酸性粒细胞性食管炎而言,需要一种可靠的非侵入性诊断生物标志物。
Lancet Gastroenterol Hepatol. 2022 Mar;7(3):202-203. doi: 10.1016/S2468-1253(21)00468-4.
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Front Pediatr. 2022 Jan 20;9:820192. doi: 10.3389/fped.2021.820192. eCollection 2021.
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