Sadoul G D, Beuret T M
Lasers Surg Med. 1986;6(2):110-8. doi: 10.1002/lsm.1900060204.
During the past 6 years, we have managed 633 cervical intraepithelial neoplasias with the CO2 laser. If the lesion is located on the ectocervix, the CO2 laser is used to vaporize it under the microscope. If the lesion is located in the endocervical canal, the CO2 laser is used to excise a cylinder-shaped tissue with a handpiece. Colposcopic examination is performed 21 days after treatment. Persistent disease is recognized at this examination; healing is obtained spontaneously in 66% of those with persistent disease without second treatment. There were eight with recurrent disease with abnormal Pap tests and abnormal colposcopic findings, and 12 with recurrent disease with abnormal Pap tests and normal colposcopic findings (recurrent koilocytis cells). After laser treatment cervical function was good and pregnancies were normal.
在过去6年里，我们用二氧化碳激光治疗了633例宫颈上皮内瘤变。如果病变位于宫颈外口，在显微镜下用二氧化碳激光将其汽化。如果病变位于宫颈管内，则用二氧化碳激光通过手持器械切除柱状组织。治疗后21天进行阴道镜检查。在这次检查中发现持续性病变；66%有持续性病变的患者未经二次治疗即自行愈合。有8例复发病例巴氏试验异常且阴道镜检查结果异常，12例复发病例巴氏试验异常但阴道镜检查结果正常（复发性挖空细胞）。激光治疗后宫颈功能良好，妊娠情况正常。
