Dwyer D E, O'Flaherty S, Packham D, Cunningham A L
Med J Aust. 1986 Jun 23;144(13):714-5. doi: 10.5694/j.1326-5377.1986.tb113705.x.
Two cases are reported of severe encephalitis in infants that were caused by a primary infection with herpes simplex virus type 1. Both patients presented with focal seizures; the clinical diagnosis was confirmed by the rapid appearance of IgM antibody to herpes simplex virus type 1 in cerebrospinal fluid and serum. In spite of the early use of acyclovir, which was administered by the intravenous route, the clinical response was poor and both infants were left with severe neurological impairment.
报告了两例由1型单纯疱疹病毒原发性感染引起的婴儿严重脑炎病例。两名患者均出现局灶性癫痫发作；脑脊液和血清中快速出现1型单纯疱疹病毒IgM抗体证实了临床诊断。尽管早期静脉注射使用了阿昔洛韦，但临床反应不佳，两名婴儿均遗留严重神经功能障碍。
