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新型低水平经皮电神经刺激器对老年口干症患者唾液分泌的刺激作用。

Salivary stimulatory effect of novel low level transcutaneous electro neurostimulator in geriatric patients with xerostomia.

机构信息

Department of Oral Biology, Saveetha Dental College, Chennai, India.

Department of Oral Pathology, SRM Dental College, Chennai, India.

出版信息

BMC Oral Health. 2023 May 28;23(1):334. doi: 10.1186/s12903-023-03049-0.

Abstract

BACKGROUND

Xerostomia (dryness of the mouth) is one of the most common long-term consequences of ageing, and it causes a tremendous impact on the function and morphology of the salivary ductal system. As a consequence, it leads to a decrease in the amount of salivary output and also affects the overall quality of life. The purpose of this study was to determine whether electrostimulation using a custom designed transcutaneous electrical nerve stimulation (TENS) device will help to improve the quality of secreted saliva following electrostimulation.

METHODS

One hundred thirty-five participants underwent the intervention for three months, twice daily (80 Hz). Pre-intervention and post-intervention unstimulated saliva were collected. Parameters such as salivary pH, cortisol level, salivary antioxidants, total protein, the viscosity of saliva, and microbial carriage were analysed.

RESULTS

Salivary pH, cortisol, microbial cultures, viscosity, and antioxidants showed a significant difference at the end of the 3rd month (p < 0.05). Irrespective of the patient's age, gender, and common underlying systemic illnesses (diabetes and hypertension), a significant change in the quality of the salivary analytes was observed.

CONCLUSION

The study emphasises the use of a custom designed TENS device in improving the quality of secreted saliva among old patients with oral dryness.

摘要

背景

口干(口腔干燥)是衰老的最常见长期后果之一,它对唾液导管系统的功能和形态产生巨大影响。结果,它导致唾液分泌量减少,也影响整体生活质量。本研究旨在确定使用定制设计的经皮神经电刺激(TENS)设备进行电刺激是否有助于改善电刺激后分泌的唾液质量。

方法

135 名参与者接受了为期三个月、每日两次(80Hz)的干预。在干预前和干预后收集未刺激的唾液。分析唾液 pH 值、皮质醇水平、唾液抗氧化剂、总蛋白、唾液粘度和微生物携带等参数。

结果

唾液 pH 值、皮质醇、微生物培养物、粘度和抗氧化剂在第 3 个月末有显著差异(p<0.05)。无论患者的年龄、性别和常见的系统性疾病(糖尿病和高血压)如何,唾液分析物的质量都有显著变化。

结论

该研究强调了使用定制设计的 TENS 设备在改善老年口干患者分泌唾液质量方面的作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5158/10226253/7299f93fe8c7/12903_2023_3049_Fig1_HTML.jpg

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