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口干症对头颈部放疗患者生活质量的影响。

Impact of xerostomia on the quality of life of patients submitted to head and neck radiotherapy.

机构信息

Hospital of Cancer of Pernambuco Avenida Cruz Cabuga 1597 - Santo Amaro Recife - PE. Brazil, 50040-000

出版信息

Med Oral Patol Oral Cir Bucal. 2019 Nov 1;24(6):e770-e775. doi: 10.4317/medoral.23131.

Abstract

BACKGROUND

The aim of the present work was to evaluate the impact of xerostomia on the quality of life of patients who underwent radiotherapy in the head and neck region.

MATERIAL AND METHODS

This was a cross-sectional, quantitative study. The sample comprised 40 patients whose xerostomia was classified through the xerostomia inventory and the quality of life evaluated through the oral health impact profile questionnaire (OHIP).

RESULTS

The majority of participants were male (75%), mean age 58.7 years. According to the degree of severity of the xerostomia, the average score among the participants was 36 points, this being considered moderate xerostomia. A significant impact was observed, with the median score 11 points, with the highest scores in the domains related to functional limitation, physical pain and physical disability. The majority of the participants (97.5%) had reduced salivary flow after the end of radiotherapy. There was a significant positive correlation between the degree of xerostomia and reduced quality of life, Pearson correlation 0.5421, (p<0.05).

CONCLUSION

Based upon the results it is concluded that xerostomia has a negative impact on the quality of life of patients who undergo radiotherapy in the head and neck region.

摘要

背景

本研究旨在评估头颈部放疗患者口干对生活质量的影响。

材料与方法

这是一项横断面、定量研究。样本包括 40 名患者,通过口干量表和口腔健康影响简表(OHIP)评估其口干和生活质量。

结果

大多数参与者为男性(75%),平均年龄 58.7 岁。根据口干严重程度的程度,参与者的平均评分为 36 分,被认为是中度口干。观察到显著的影响,中位数评分为 11 分,与功能受限、身体疼痛和身体残疾相关的领域得分最高。大多数参与者(97.5%)在放疗结束后唾液流量减少。口干程度与生活质量下降呈显著正相关,皮尔逊相关系数为 0.5421(p<0.05)。

结论

基于研究结果得出结论,口干会对接受头颈部放疗的患者的生活质量产生负面影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b5a2/6901149/18ea40066f3c/medoral-24-e770-g001.jpg

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