Canama Gibson Jake C, Delco Monica Claire L, Talandron Rhoel A, Tan Noel Peter
Department of Chemical Engineering, University of San Carlos, Talamban Campus, Cebu City 6000, Philippines.
Department of Chemical Engineering, College of Technology, University of San Agustin, Iloilo City 5000, Philippines.
ACS Omega. 2023 May 10;8(20):17699-17711. doi: 10.1021/acsomega.3c00191. eCollection 2023 May 23.
An easy and environment-friendly route for antibacterial coating suited for mobile phone glass protectors was successfully demonstrated. In this route, freshly prepared chitosan solution in 1% v/v acetic acid was added with 0.1 M silver nitrate solution and 0.1 M sodium hydroxide solution and incubated with agitation at 70 °C to form chitosan-silver nanoparticles (ChAgNPs). Varied concentrations of chitosan solution (i.e., 0.1, 0.2, 0.4, 0.6, and 0.8% w/v) were used to investigate its particle size, size distribution, and later on, its antibacterial activity. Transmission electron microscope (TEM) imaging revealed that the smallest average diameter of silver nanoparticles (AgNPs) was 13.04 nm from 0.8% w/v chitosan solution. Further characterizations of the optimal nanocomposite formulation using UV-vis spectroscopy and Fourier transfer infrared spectroscopy were also performed. Using a dynamic light scattering zetasizer, the average ζ-potential of the optimal ChAgNP formulation was at +56.07 mV, showing high aggregative stability and an average ChAgNP size of 182.37 nm. The ChAgNP nanocoating on glass protectors shows antibacterial activity against (E. coli) at 24 and 48 h of contact. However, the antibacterial activity decreased from 49.80% (24 h) to 32.60% (48 h).
成功展示了一种适用于手机玻璃保护膜的简便且环保的抗菌涂层制备方法。在该方法中,将新制备的1% v/v醋酸壳聚糖溶液与0.1 M硝酸银溶液和0.1 M氢氧化钠溶液混合,在70°C下搅拌孵育以形成壳聚糖-银纳米颗粒(ChAgNPs)。使用不同浓度的壳聚糖溶液(即0.1、0.2、0.4、0.6和0.8% w/v)来研究其粒径、粒径分布以及后续的抗菌活性。透射电子显微镜(TEM)成像显示,0.8% w/v壳聚糖溶液制备的银纳米颗粒(AgNPs)平均直径最小,为13.04 nm。还使用紫外可见光谱和傅里叶变换红外光谱对最佳纳米复合材料配方进行了进一步表征。使用动态光散射zeta电位仪,最佳ChAgNP配方的平均ζ电位为+56.07 mV,显示出高聚集稳定性,平均ChAgNP粒径为182.37 nm。玻璃保护膜上的ChAgNP纳米涂层在接触24小时和48小时时对大肠杆菌显示出抗菌活性。然而,抗菌活性从49.80%(24小时)降至32.60%(48小时)。