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一例由新型冠状病毒引发的急性嗜酸性粒细胞性肺炎病例。

A Case of Acute Eosinophilic Pneumonia Triggered by the SARS-CoV-2 Virus.

作者信息

De Albuquerque Monteiro Inês, Fernandes Moura Pedro, Fernandes Diana, Carneiro José Carlos, Teixeira Sofia

机构信息

Internal Medicine, Centro Hospitalar do Médio Ave, Vila Nova de Famalicão, PRT.

Pulmonology, Centro Hospitalar do Médio Ave, Vila Nova de Famalicão, PRT.

出版信息

Cureus. 2023 Apr 25;15(4):e38111. doi: 10.7759/cureus.38111. eCollection 2023 Apr.

Abstract

We report a case of acute eosinophilic pneumonia (AEP) triggered by the coronavirus disease 2019 (COVID-19) infection. A 60-year-old male with chronic sinusitis and tobacco use presented to the emergency department (ED) with an acute onset of dyspnea, non-productive cough, and fever. A diagnosis of moderate SARS-CoV-2 infection with bacterial superinfection was made. He was discharged on antibiotic therapy. One month later, due to the persistence of symptoms, he returned to the ED. At this time, blood analysis showed eosinophilia and a chest computed tomography scan showed bilateral diffuse infiltrative changes. He was admitted to the hospital for the study of eosinophilic disease. A lung biopsy was performed, which showed eosinophilic pneumonia. Corticotherapy was started with symptoms and peripheral eosinophilia resolution, and imaging improvement.

摘要

我们报告一例由2019冠状病毒病(COVID-19)感染引发的急性嗜酸性粒细胞性肺炎(AEP)。一名60岁男性,有慢性鼻窦炎且吸烟,因急性起病的呼吸困难、干咳和发热就诊于急诊科(ED)。诊断为中度严重急性呼吸综合征冠状病毒2型(SARS-CoV-2)感染合并细菌重叠感染。给予抗生素治疗后出院。一个月后,因症状持续存在,他再次回到急诊科。此时,血液分析显示嗜酸性粒细胞增多,胸部计算机断层扫描显示双侧弥漫性浸润性改变。他因嗜酸性粒细胞疾病入院进一步检查。进行了肺活检,结果显示为嗜酸性粒细胞性肺炎。开始皮质激素治疗后,症状、外周血嗜酸性粒细胞增多情况得到缓解,影像学表现也有所改善。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9e09/10211398/ebb932b4acdf/cureus-0015-00000038111-i01.jpg

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