Department of Plant Pathology and Weed Research, Agricultural Research Organization-The Volcani Institute, Rishon LeZion, Israel; email:
Department of Plant Biology and Genome Center, College of Biological Sciences, University of California, Davis, California, USA.
Annu Rev Virol. 2023 Sep 29;10(1):455-476. doi: 10.1146/annurev-virology-111821-122847. Epub 2023 May 30.
Plant viruses of the genus cause significant economic losses in various crops. The emergence of new tobamoviruses such as the tomato brown rugose fruit virus (ToBRFV) poses a major threat to global agriculture. Upon infection, plants mount a complex immune response to restrict virus replication and spread, involving a multilayered defense system that includes defense hormones, RNA silencing, and immune receptors. To counter these defenses, tobamoviruses have evolved various strategies to evade or suppress the different immune pathways. Understanding the interactions between tobamoviruses and the plant immune pathways is crucial for the development of effective control measures and genetic resistance to these viruses. In this review, we discuss past and current knowledge of the intricate relationship between tobamoviruses and host immunity. We use this knowledge to understand the emergence of ToBRFV and discuss potential approaches for the development of new resistance strategies to cope with emerging tobamoviruses.
植物弹状病毒属的病毒会给各种作物造成重大经济损失。新的烟草花叶病毒如番茄褐色皱果病毒（ToBRFV）的出现对全球农业构成了重大威胁。感染后，植物会启动复杂的免疫反应来限制病毒的复制和传播，涉及包括防御激素、RNA 沉默和免疫受体在内的多层次防御系统。为了对抗这些防御，烟草花叶病毒进化出了各种策略来逃避或抑制不同的免疫途径。了解烟草花叶病毒与植物免疫途径之间的相互作用对于开发有效的控制措施和遗传抗性来对抗这些病毒至关重要。在这篇综述中，我们讨论了烟草花叶病毒与宿主免疫之间复杂关系的过去和当前知识。我们利用这些知识来了解 ToBRFV 的出现，并讨论开发新的抗性策略的潜在方法，以应对新兴的烟草花叶病毒。
