Mimouni F, Han B K, Barnes L, Ballard J L, Dignan P S, Kiessling M A, Lucky A W
Pediatr Dermatol. 1986 Jun;3(3):219-25. doi: 10.1111/j.1525-1470.1986.tb00517.x.
We examined a newborn infant with multiple hamartomas, including an epidermal nevus syndrome and a giant pigmented congenital nevocellular nevus, associated with other structural developmental abnormalities such as nevus flammeus, vascular malformation, cutis aplasia congenita of the scalp, cartilage hamartoma, and a lipodermoid of the conjunctiva. This child had a significant brain malformation, diagnosed by sonography and computerized tomography, consisting of a significant enlargement of the left hemisphere not associated with asymmetry of the skull or facial bones. We suggest a careful investigation of the intracranial structures by computerized tomography and/or ultrasonography in case of either extensive linear nevus sebaceous sequence and/or giant pigmented nevocellular nevus.
我们检查了一名患有多种错构瘤的新生儿，包括表皮痣综合征和巨大先天性色素性痣细胞痣，同时伴有其他结构发育异常，如鲜红斑痣、血管畸形、头皮先天性皮肤发育不全、软骨错构瘤以及结膜皮样脂肪瘤。通过超声检查和计算机断层扫描诊断出该患儿存在严重的脑畸形，表现为左半球显著增大，而颅骨或面部骨骼并无不对称。我们建议，对于患有广泛线性皮脂腺痣序列和/或巨大色素性痣细胞痣的患者，应通过计算机断层扫描和/或超声检查对颅内结构进行仔细检查。
