Kaplan H, Lacentre E
Med Cutan Ibero Lat Am. 1986;14(6):413-20.
A case is reported of complex hamartoma with the aspect of a giant pigmented nevus, localized in one of the lower extremities. Histological examination revealed the involvement of different embryonal layers in order to give rise to dissimilar types of nevi: flat pigmented nevus, intradermal cellular nevus, epidermal verrucous nevus, Jadassohn's sebaceous nevus; Hoffman-Zurhelle's superficial lipomatous nevus, and fibrous hamartoma of the manifested at infancy. This malformation and more specifically the nevus cells constitute the subsequent transformation into an infiltrating malignant blastoma (malignant melanoma).
报告了一例表现为巨大色素痣的复杂错构瘤病例，位于一侧下肢。组织学检查显示不同胚胎层受累，从而产生不同类型的痣：扁平色素痣、皮内细胞痣、表皮疣状痣、雅达逊皮脂腺痣、霍夫曼 - 祖尔赫尔浅表脂肪瘤样痣，以及婴儿期出现的纤维错构瘤。这种畸形，更具体地说是痣细胞，构成了随后转变为浸润性恶性母细胞瘤（恶性黑色素瘤）的基础。
