Hackenberger F, Gabrio T, Grune D, Bornschein M, Dietzsch B, Voigt R
Pharmazie. 1986 Apr;41(4):244-7.
The examination of the bioavailability from 4 different preparations of propyphenazone suppositories on a fatty base, studied in 10 healthy volunteers, showed bioequivalence as was judged by means of the AUC-values. Aminophenazone suppositories of an equivalent dosage led to significant higher values of plasma concentrations if compared with propyphenazone. The in vivo findings correlate with in vitro results of availability.
在10名健康志愿者身上对4种不同的丙氧苯宗脂肪基质栓剂制剂的生物利用度进行了研究，通过AUC值判断，结果显示生物等效性。与丙氧苯宗相比，同等剂量的氨基比林栓剂导致血浆浓度值显著更高。体内研究结果与体外可用性结果相关。
