Shekerdjiiski R, Paskov V, Lambov N, Gencheva P, Rachev D, Titeva S, Minkov E
Pharmazie. 1987 Mar;42(3):184-6.
Studies were performed with oral dosage formulations of propyphenazon, i.e. aqueous suspension (1%), instant suspension (1%) and tablets (100 mg) for pediatric use. The influence of the pharmaceutical adjuvants of the release of the drug from the model preparations was established. The biological availability determined from rabbits showed that the formulated preparations are biologically equivalent.
对丙苯唑酮的口服剂型进行了研究,即儿科用的水悬浮液(1%)、速溶悬浮液(1%)和片剂(100毫克)。确定了模型制剂中药物辅料对药物释放的影响。从兔子身上测定的生物利用度表明,所配制的制剂在生物等效性方面是相当的。