Bioinformatics Unit, International Centre for Genetic Engineering and Biotechnology, Cape Town, South Africa.
Faculty of Medical Laboratory Science, Department of Histopathology and Cytology, IBN SINA University, Khartoum, Sudan.
Methods Mol Biol. 2023;2675:195-204. doi: 10.1007/978-1-0716-3247-5_15.
Nuclear magnetic resonance (NMR) spectroscopy enables the detection and the quantification of a large range of molecules, including low-molecular-weight metabolites and lipids. NMR spectroscopy is a powerful approach when applied to the high-throughput analysis of plasma or serum samples allowing, in addition, the detection of total proteins, lipoproteins, and signals arising from the glycosylation of circulating acute-phase proteins. Here, we describe the usage of NMR spectroscopy for profiling the plasma or serum of patients with prostate cancer.
核磁共振(NMR)光谱技术可用于检测和定量分析多种分子,包括低分子量代谢物和脂质。当应用于高通量分析血浆或血清样本时,NMR 光谱技术是一种强大的方法,此外还可以检测总蛋白、脂蛋白和循环急性期蛋白糖基化产生的信号。本文介绍了使用 NMR 光谱技术对前列腺癌患者的血浆或血清进行分析。