LEAF - Linking Landscape, Environment, Agriculture and Food Research Center, Associated Laboratory TERRA, Instituto Superior de Agronomia, Universidade de Lisboa, Tapada da Ajuda, 1349-017, Lisboa, Portugal.
CIISA - Centre for Interdisciplinary Research in Animal Health, Faculdade de Medicina Veterinária, Universidade de Lisboa, 1300-477, Lisboa, Portugal.
Sci Rep. 2023 May 31;13(1):8784. doi: 10.1038/s41598-023-36008-4.
Ulva lactuca is a seaweed with antinutritional cell wall for monogastrics. Carbohydrate-Active enZymes (CAZymes) supplementation can potentially cause its disruption. This study evaluates four diets: Ctrl-control diet; UL-control + 7% U. lactuca (wild caught, powdered form); ULR-UL + 0.005% Rovabio Excel AP; ULU-UL + 0.01% ulvan lyase on piglets' haematologic and serologic profiles, hepatic lipids and minerals. White blood cells and lymphocytes reached the highest values in piglets fed UL compared to control, and to control and ULR; respectively (P < 0.05). IgG levels were boosted by seaweed incorporation compared to control (P = 0.015). The glycaemic homeostasis was assured by the seaweed inclusion. Dietary seaweed decreased serum lipids (P < 0.001), with the exception of ULU, due to HDL-cholesterol increase (P < 0.001). Cortisol was decreased in ULR and ULU (P < 0.001). No systemic inflammation was observed (P > 0.05). While hepatic n-3 PUFA increased in piglets fed with seaweed diets due to increment of beneficial 22:5n-3 and 22:6n-3 fatty acids (P < 0.05), the opposite occurred for n-6 PUFA, PUFA/SFA and n-6/n-3 ratios (P < 0.05). Hepatic pigments were unchanged (P > 0.05). ULR reduced α-tocopherol levels (P = 0.036) and increased serum potassium levels (P < 0.001) compared to control. Seaweed contributed to overcome piglets' weaning stress, with some benefits of including CAZyme supplementation.
绿球藻是一种具有抗营养细胞壁的海藻，适合单胃动物。碳水化合物活性酶（CAZymes）的补充可能会导致其破坏。本研究评估了四种日粮：对照日粮（Ctrl-control diet）；对照+7%（野生捕捞，粉末形式）的绿球藻（UL-control+7% U. lactuca）；对照+0.005% Rovabio Excel AP（ULR-UL+0.005% Rovabio Excel AP）；对照+0.01%岩藻聚糖裂解酶（ULU-UL+0.01% ulvan lyase）对仔猪血液学和血清学特征、肝脏脂质和矿物质的影响。与对照和 ULR 相比，饲喂绿球藻的仔猪的白细胞和淋巴细胞达到最高值（P<0.05）。与对照相比，添加海藻可提高 IgG 水平（P=0.015）。海藻的添加确保了血糖的稳态。膳食海藻降低了血清脂质（P<0.001），但 ULU 除外，因为 HDL-胆固醇增加（P<0.001）。URL 和 ULU 组的皮质醇降低（P<0.001）。未观察到全身炎症（P>0.05）。由于有益的 22:5n-3 和 22:6n-3 脂肪酸增加，饲喂海藻日粮的仔猪肝脏 n-3 PUFA 增加（P<0.05），而 n-6 PUFA、PUFA/SFA 和 n-6/n-3 比值则相反（P<0.05）。肝色素不变（P>0.05）。与对照相比，URL 降低了 α-生育酚水平（P=0.036）并增加了血清钾水平（P<0.001）。海藻有助于克服仔猪断奶应激，添加 CAZyme 补充剂也有一些益处。
