CIISA - Centro de Investigação Interdisciplinar em Sanidade Animal, Faculdade de Medicina Veterinária, Universidade de Lisboa, Pólo Universitário do Alto da Ajuda, Av. da Universidade Técnica, 1300-477, Lisbon, Portugal.
LEAF - Linking Landscape, Environment, Agriculture and Food, Instituto Superior de Agronomia, Universidade de Lisboa, Tapada da Ajuda, 1349-017, Lisbon, Portugal.
BMC Vet Res. 2021 Apr 13;17(1):158. doi: 10.1186/s12917-021-02869-y.
The ability of a high level of dietary Arthrospira platensis, individually or in combination with two exogenous carbohydrate-degrading enzymes (lysozyme and Rovabio), to improve systemic antioxidant potential and hepatic lipid metabolism was tested in piglets. Forty male post-weaned piglets, sons of Large White × Landrace sows crossed with Pietrain boars, were allocated into 4 groups (n = 10) and fed during 28 days one of the following diets: 1) a control basal diet (cereal and soybean meal); 2) a basal diet with 10% of A. platensis (AP); 3) the AP diet supplemented with 0.005% of Rovabio (AP + R); 4) the AP diet supplemented with 0.01% of lysozyme (AP + L).
Arthrospira platensis decreased BW gain of piglets, regardless the addition of feed enzymes. The majority of plasma metabolites were affected by diets. A. platensis increased total lipids, total cholesterol and LDL-cholesterol, without changing hepatic fatty acid content or modulating, in an expressive manner, the transcriptional profile of lipid sensitive mediators. The antioxidant potential in general, and total carotenoids in particular, were improved by the microalga, regardless lysozyme or Rovabio.
Summing up, A. platensis, individually and combined with feed enzymes, impacts negatively on piglets' growth but improves the systemic antioxidant potential and changes plasma lipids with a minor modulation on related hepatic metabolic pathways.
高含量的螺旋藻（Arthrospira platensis），无论是单独使用还是与两种外源碳水化合物降解酶（溶菌酶和 Rovabio）联合使用，都被测试其改善仔猪系统抗氧化能力和肝脏脂质代谢的能力。40 头断奶后的雄性仔猪，大白猪×长白猪与皮特兰公猪杂交的后代，被分配到 4 组（n = 10），并在 28 天内分别饲喂以下日粮之一：1）对照基础日粮（谷物和豆粕）；2）基础日粮添加 10%的螺旋藻（AP）；3）AP 日粮添加 0.005%的 Rovabio（AP + Rovabio）；4）AP 日粮添加 0.01%的溶菌酶（AP + 溶菌酶）。
无论是否添加饲料酶，螺旋藻都降低了仔猪的体重增加。大多数血浆代谢物受到日粮的影响。螺旋藻增加了总脂质、总胆固醇和 LDL 胆固醇，而不改变肝脂肪酸含量，也不以显著方式调节脂质敏感介质的转录谱。总的抗氧化能力，特别是总类胡萝卜素，均因微藻而得到改善，而与溶菌酶或 Rovabio 无关。
总之，螺旋藻单独使用或与饲料酶联合使用，对仔猪的生长有负面影响，但能提高系统抗氧化能力，并改变血浆脂质，对相关的肝脏代谢途径有较小的调节作用。
