Fantino M, Brinnel H
Physiol Behav. 1986;36(6):991-6. doi: 10.1016/0031-9384(86)90469-5.
Body weight, food intake and food hoarding behavior were measured in 12 female rats fed ad lib and correlated with the ovarian cycle of each. All three parameters fluctuated synchronously, being minimal at estrus and maximal at diestrus. The hypothesis was then tested that these fluctuations result from cyclical oscillation of the body weight set-point entrained by the ovarian cycle, as previously proposed by others. The linear correlation between hoarding behavior and body weight was used to extrapolate the computed threshold of body weight at which hoarding behavior occurred at diestrus and at estrus; this threshold has already been shown to be a good index of the body weight set-point. The results indicated that the regression of hoarding behavior on body weight was virtually identical at estrus and diestrus (same slope), but the critical level of body weight for the onset of hoarding behavior was 31.2 g lower at estrus than at diestrus. This provides direct evidence in the rat of fluctuation of the body weight set-point with the ovarian cycle.
对12只自由采食的雌性大鼠测量了体重、食物摄入量和食物贮藏行为，并将其与每只大鼠的卵巢周期进行关联。所有这三个参数同步波动，在发情期最小，在动情间期最大。然后检验了这样一个假设：如其他人之前所提出的，这些波动是由卵巢周期所带动的体重设定点的周期性振荡导致的。贮藏行为与体重之间的线性相关性被用于推断在动情间期和发情期发生贮藏行为时计算出的体重阈值；这个阈值已被证明是体重设定点的一个良好指标。结果表明，发情期和动情间期贮藏行为对体重的回归几乎相同（斜率相同），但贮藏行为开始时的临界体重水平在发情期比在动情间期低31.2克。这为大鼠体重设定点随卵巢周期波动提供了直接证据。
