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新生儿重症监护病房胃肠外给药的良好操作规范——一个跨学科工作组的立场文件

Good handling practice of parenterally administered medicines in neonatal intensive care units - position paper of an interdisciplinary working group.

作者信息

Krämer Irene, Goelz Rangmar, Gille Christian, Härtel Christoph, Müller Rachel, Orlikowsky Thorsten, Piening Brar, Schubert Sebastian, Simon Arne, Wolf Katharina, Rösner Bianka, Exner Martin

机构信息

Department of Pharmacy, University Medical Center, Johannes Gutenberg University Mainz, Mainz, Germany.

Department of Neonatology, Tübingen University Children's Hospital, Tübingen, Germany.

出版信息

GMS Hyg Infect Control. 2023 May 3;18:Doc10. doi: 10.3205/dgkh000436. eCollection 2023.

DOI:10.3205/dgkh000436
PMID:37261055
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10227494/
Abstract

This position paper, developed by an interdisciplinary expert group of neonatologists, paediatric infectious disease physicians, clinical pharmacists and specialists for the prevention and control of nosocomial infections, describes the "Good handling practice of medicines parenterally administered to patients on NICUs". It takes equal account of patient safety and the specialties of neonatal intensive care regarding feasibility and proportionality. The overall concept is perceived as a "learning system", in which open communication within the health-care team relating to medication errors and critical incidents enables continuous development and improvement to ensure patient safety. In our opinion, pharmacists, who are responsible for the supply of ready-to-administer parenteral medicinal products for neonatal intensive care patients, as well as the hygiene staff responsible on site are integral parts of the interdisciplinary treatment team. Risks of the current clinical practice of parenteral treatment of NICU patients are discussed in detail and recommendations for safety-relevant procedures are given.

摘要

这份立场文件由新生儿科医生、儿科传染病医生、临床药剂师以及医院感染预防与控制专家组成的跨学科专家组制定,阐述了“新生儿重症监护病房(NICU)患者静脉用药的良好操作规范”。它在可行性和相称性方面兼顾了患者安全以及新生儿重症监护的特殊性。整体理念被视为一个“学习系统”,在这个系统中,医疗团队内部就用药错误和危急事件进行开放沟通,能够实现持续发展和改进,以确保患者安全。我们认为,负责为新生儿重症监护患者供应即用型静脉注射药品的药剂师以及现场负责的卫生工作人员是跨学科治疗团队的重要组成部分。文中详细讨论了目前NICU患者静脉治疗临床实践中的风险,并给出了与安全相关程序的建议。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3309/10227494/5e84fe3c70cb/HIC-18-10-t-002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3309/10227494/0cb585e4758f/HIC-18-10-t-001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3309/10227494/5e84fe3c70cb/HIC-18-10-t-002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3309/10227494/0cb585e4758f/HIC-18-10-t-001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3309/10227494/5e84fe3c70cb/HIC-18-10-t-002.jpg

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Drug compatibility in neonatal intensive care units: gaps in knowledge and discordances.新生儿重症监护病房的药物相容性:知识差距和不和谐。
Eur J Pediatr. 2021 Jul;180(7):2305-2313. doi: 10.1007/s00431-021-04028-9. Epub 2021 Mar 18.
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The impact of introducing automated dispensing cabinets, barcode medication administration, and closed-loop electronic medication management systems on work processes and safety of controlled medications in hospitals: A systematic review.
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Res Social Adm Pharm. 2021 May;17(5):832-841. doi: 10.1016/j.sapharm.2020.08.001. Epub 2020 Sep 2.
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Dosing of Antimicrobials in the Neonatal Intensive Care Unit: Does Clinical Practice Reflect Pharmacokinetics-based Recommendations?新生儿重症监护病房中抗菌药物的给药剂量:临床实践是否反映了基于药代动力学的推荐?
Pediatr Infect Dis J. 2020 Aug;39(8):713-717. doi: 10.1097/INF.0000000000002657.
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