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[下莱茵省常规开具的抗结核治疗方案及治疗结果]

[Antitubercular therapeutic regimens routinely prescribed in Bas-Rhin and results of treatment].

作者信息

Liard R, Perdrizet S, Burghard G, Petitjean R, Rempp M, Pierau F, Chenuet J

出版信息

Rev Mal Respir. 1986;3(2):93-7.

PMID:3726265
Abstract

The overall plans and therapeutic regimens prescribed for new cases of pulmonary tuberculosis notified in the Bas-Rhin in 1979 to 1980 (372 Subjects) were studied, as were relapses occurring over a three year period from the date of notification. As in the preceding analysis of cases between 1970/78, the proportion of patients treated exclusively at home was low (22.8%) and the duration of stay in a Sanatorium was lengthy (mean 86.6 days for cases without bacteriological confirmation and 142.3 days for bacteriologically positive cases). The mean duration of chemotherapy was 12.5 months (+/- 3.7). The therapeutic regimens prescribed showed a significant variability: if 80.6% of patients received, at one time or another, the combination of Isoniazid (H), Rifampicin (R) and Ethambutol (E), only 33.9% of the adults treated received the HRE/HR regimen, for periods of variable duration. Four relapses were seen during the fixed follow-up period.

摘要

对1979年至1980年在下莱茵省通报的肺结核新病例(372例)所规定的总体计划和治疗方案进行了研究,并对自通报之日起三年内发生的复发情况进行了研究。与之前对1970/78年病例的分析一样,仅在家接受治疗的患者比例较低(22.8%),疗养院住院时间较长(无细菌学确认的病例平均为86.6天,细菌学阳性病例为142.3天)。化疗的平均持续时间为12.5个月(±3.7)。所规定的治疗方案显示出显著差异:尽管80.6%的患者曾一度接受异烟肼(H)、利福平(R)和乙胺丁醇(E)的联合治疗,但接受HRE/HR方案治疗的成年患者中,只有33.9%接受了不同疗程的该方案治疗。在固定随访期内发现了4例复发。

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