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评估苏格兰最低单位定价对有害饮酒流行率的影响:一项对照中断时间序列分析。

Evaluating the effects of minimum unit pricing in Scotland on the prevalence of harmful drinking: a controlled interrupted time series analysis.

机构信息

Sheffield Alcohol Research Group, School of Health and Related Research (ScHARR), University of Sheffield, UK.

School of Health and Wellbeing, University of Glasgow, UK.

出版信息

Public Health. 2023 Jul;220:43-49. doi: 10.1016/j.puhe.2023.04.019. Epub 2023 May 31.

DOI:10.1016/j.puhe.2023.04.019
PMID:37263177
Abstract

OBJECTIVES

In May 2018, the Scottish Government introduced a minimum unit price (MUP) for alcohol of £0.50 (1 UK unit = 8 g ethanol) to reduce alcohol consumption, particularly among people drinking at harmful levels. This study aimed to evaluate MUP's impact on the prevalence of harmful drinking among adults in Scotland.

STUDY DESIGN

This was a controlled interrupted monthly time series analysis of repeat cross-sectional data collected via 1-week drinking diaries from adult drinkers in Scotland (N = 38,674) and Northern England (N = 71,687) between January 2009 and February 2020.

METHODS

The primary outcome was the proportion of drinkers consuming at harmful levels (>50 [men] or >35 [women] units in diary week). The secondary outcomes included the proportion of drinkers consuming at hazardous (≥14-50 [men] or ≥14-35 [women] units) and moderate (<14 units) levels and measures of beverage preferences and drinking patterns. Analyses also examined the prevalence of harmful drinking in key subgroups.

RESULTS

There was no significant change in the proportion of drinkers consuming at harmful levels (β = +0.6 percentage points; 95% confidence interval [CI] = -1.1, +2.3) or moderate levels (β = +1.4 percentage points; 95% confidence interval = -1.1, +3.8) after the introduction of MUP. The proportion consuming at hazardous levels fell significantly by 3.5 percentage points (95% CI = -5.4, -1.7). There were no significant changes in other secondary outcomes or in the subgroup analyses after correction for multiple testing.

CONCLUSIONS

Introducing MUP in Scotland was not associated with reductions in the proportion of drinkers consuming at harmful levels but did reduce the prevalence of hazardous drinking. This adds to previous evidence that MUP reduced overall alcohol consumption in Scotland and consumption among those drinking above moderate levels.

摘要

目的

2018 年 5 月,苏格兰政府出台了酒精最低单位价格(MUP)政策,规定每单位 0.50 英镑(1 英国单位=8 克乙醇),以减少酒精消费,尤其是针对那些饮酒量达到有害水平的人群。本研究旨在评估 MUP 对苏格兰成年人有害饮酒流行率的影响。

研究设计

这是一项基于苏格兰和英格兰北部成年人饮酒者重复横断面数据的对照干预月度时间序列分析,数据收集方式为每周 1 天的饮酒日记,时间跨度为 2009 年 1 月至 2020 年 2 月(N=38674)。

方法

主要结局指标为有害饮酒者的比例(男性每周饮酒量超过 50 单位,女性超过 35 单位)。次要结局指标包括有害(男性每周饮酒量超过 14-50 单位,女性超过 14-35 单位)和适量(男性每周饮酒量<14 单位,女性<14 单位)饮酒者的比例以及饮料偏好和饮酒模式的衡量指标。分析还考察了关键亚组人群中有害饮酒的流行率。

结果

MUP 实施后,有害饮酒者的比例(β=+0.6 个百分点;95%置信区间[CI]为-1.1,2.3)或适量饮酒者的比例(β=+1.4 个百分点;95%CI 为-1.1,3.8)均无显著变化。危险饮酒者的比例显著下降 3.5 个百分点(95%CI 为-5.4,-1.7)。在进行多次检验校正后,其他次要结局或亚组分析中均未出现显著变化。

结论

苏格兰实施 MUP 政策与降低有害饮酒者的比例无关,但确实降低了危险饮酒的流行率。这与之前的证据一致,即 MUP 减少了苏格兰的总体酒精消费以及高于适量饮酒者的饮酒量。

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