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COPD 中的诊断肺量测定术正在增加,两个瑞典队列的比较。

Diagnostic spirometry in COPD is increasing, a comparison of two Swedish cohorts.

机构信息

School of Medical Sciences, Faculty of Medicine and Health, Örebro University, Örebro, Sweden.

Department of Public Health and Caring Sciences, Family Medicine and Preventive Medicine, Uppsala University, Uppsala, Sweden.

出版信息

NPJ Prim Care Respir Med. 2023 Jun 2;33(1):23. doi: 10.1038/s41533-023-00345-8.

Abstract

Spirometry should be used to confirm a diagnosis of chronic obstructive pulmonary disease (COPD). This test is not always performed, leading to possible misdiagnosis. We investigated whether the proportion of patients with diagnostic spirometry has increased over time as well as factors associated with omitted or incorrectly interpreted spirometry. Data from medical reviews and a questionnaire from primary and secondary care patients with a doctors' diagnosis of COPD between 2004 and 2010 were collected. Data were compared with a COPD cohort diagnosed between 2000 and 2003. Among 703 patients with a first diagnosis of COPD between 2004 and 2010, 88% had a diagnostic spirometry, compared with 59% (p < 0.001) in the previous cohort. Factors associated with not having diagnostic spirometry were current smoking (OR 2.21; 95% CI 1.36-3.60), low educational level (OR 1.81; 1.09-3.02) and management in primary care (OR 2.28; 1.02-5.14). The correct interpretation of spirometry results increased (75% vs 82%; p = 0.010). Among patients with a repeated spirometry, 94% had a persistent FEV/FVC or FEV/VC ratio <0.70.

摘要

肺量测定法应该用于确诊慢性阻塞性肺病(COPD)。但这项检查并非一直进行,可能导致误诊。我们调查了随着时间的推移,接受诊断性肺量测定法的患者比例是否有所增加,以及与漏检或错误解读肺量测定法相关的因素。研究收集了 2004 年至 2010 年间在初级和二级保健机构就诊、被医生诊断为 COPD 的患者的病历回顾和问卷调查数据,与 2000 年至 2003 年确诊的 COPD 队列进行了比较。在 2004 年至 2010 年间首次被诊断为 COPD 的 703 名患者中,88%接受了诊断性肺量测定法,而前一个队列中这一比例为 59%(p<0.001)。未进行诊断性肺量测定法的相关因素包括当前吸烟(OR 2.21;95%CI 1.36-3.60)、教育程度较低(OR 1.81;1.09-3.02)和在初级保健机构治疗(OR 2.28;1.02-5.14)。肺量测定法结果的正确解读率有所增加(75%对 82%;p=0.010)。在重复进行肺量测定法的患者中,94%的患者仍存在 FEV/FVC 或 FEV/VC 比值<0.70。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2ab8/10235108/f70dbfae4bfe/41533_2023_345_Fig1_HTML.jpg

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