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在服务不足的患者人群中过度诊断慢性阻塞性肺疾病。

Over diagnosis of chronic obstructive pulmonary disease in an underserved patient population.

机构信息

Department of Internal Medicine, St Elizabeth Health Center, Youngstown, OH, USA.

Northeast Ohio Medical University College of Pharmacy, Rootstown, OH, USA.

出版信息

Int J Chron Obstruct Pulmon Dis. 2013;8:545-9. doi: 10.2147/COPD.S45693. Epub 2013 Nov 12.

Abstract

INTRODUCTION

While cross-national studies have documented rates of chronic obstructive pulmonary disease (COPD) misdiagnosis among patients in primary care, US studies are scarce. Studies investigating diagnosis among uninsured patients are lacking.

OBJECTIVE

The purpose of this study is to identify patients who are over diagnosed and thus, mistreated, for COPD in a federally qualified health center.

METHODS

A descriptive study was conducted for a retrospective cohort from February 2011 to June 2012. Spirometry was performed by trained personnel following American Thoracic Society recommendations. Patients were referred for spirometry to confirm previous COPD diagnosis or to assess uncontrolled COPD symptoms. Airway obstruction was defined as a forced expiratory volume in the first second of expiration (FEV1) to forced vital capacity ratio less than 0.7. Reversibility was defined as a postbronchodilator increase in FEV1 greater than 200 mL and greater than 12%.

RESULTS

Eighty patients treated for a previous diagnosis of COPD (n = 72) or on anticholinergic inhalers (n = 8) with no COPD diagnosis were evaluated. The average age was 52.9 years; 71% were uninsured. Only 17.5% (14/80) of patients reported previous spirometry. Spirometry revealed that 42.5% had no obstruction, 22.5% had reversible obstruction, and 35% had non-reversible obstruction.

CONCLUSION

Symptoms and smoking history are insufficient to diagnose COPD. Prevalence of COPD over diagnosis among uninsured patient populations may be higher than previously reported. Confirming previous COPD diagnosis with spirometry is essential to avoid unnecessary and potentially harmful treatment.

摘要

简介

尽管跨国研究已经记录了初级保健中慢性阻塞性肺疾病(COPD)误诊的发生率,但美国的研究却很少。缺乏针对未参保患者的诊断研究。

目的

本研究旨在确定在联邦合格的健康中心中,哪些患者因 COPD 被过度诊断和治疗不当。

方法

对 2011 年 2 月至 2012 年 6 月期间的回顾性队列进行了描述性研究。按照美国胸科学会的建议,由经过培训的人员进行肺量测定。将患者转诊进行肺量测定以确认先前的 COPD 诊断或评估未得到控制的 COPD 症状。气道阻塞定义为呼气第一秒用力呼气量(FEV1)与用力肺活量的比值小于 0.7。可变性定义为支气管扩张剂后 FEV1 增加大于 200 毫升和大于 12%。

结果

对 72 例因先前诊断为 COPD 而接受治疗的患者(n = 72)或因未诊断出 COPD 而接受抗胆碱能吸入器治疗的 8 例患者(n = 8)进行了评估。平均年龄为 52.9 岁;71%的患者没有保险。只有 17.5%(14/80)的患者报告了以前的肺量测定。肺量测定显示,42.5%的患者无阻塞,22.5%的患者有可逆性阻塞,35%的患者有不可逆性阻塞。

结论

症状和吸烟史不足以诊断 COPD。未参保患者人群中 COPD 过度诊断的患病率可能高于先前报道的。通过肺量测定确认以前的 COPD 诊断对于避免不必要和潜在有害的治疗至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/032f/3848507/6ec5e9a6efcd/copd-8-545Fig1.jpg

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