Enarson D A, Chan-Yeung M, Embree V, Wang R, Schulzer M
Scand J Work Environ Health. 1986 Apr;12(2):144-8. doi: 10.5271/sjweh.2165.
A group of 71 chlorophenate-exposed sawmill workers were identified as part of a group undergoing an extensive health and environmental evaluation in a pulp mill. This group was compared with a group (N = 351) with no physical proximity to the area in which chlorophenates were used. Exposure was higher for those directly handling the wood and lower for those working in the area but not handling the wood. Those with chlorophenate exposure were not significantly more likely to report a history of jaundice or liver, kidney or heart disease. Moreover, the serum creatinine, bilirubin, glutamic oxaloacetic transaminase (GOT), and alkaline phosphatase values did not differ from those of the reference group. The hemoglobin level was similar in the three groups. But the peripheral blood leukocyte count was marginally lower in the exposed groups and their hematocrit was reduced, significantly so for the heavily exposed group. Urinalysis showed an increased prevalence of microscopic hematuria, especially with lower cell counts. No unequivocal explanation is available for the reduced hematocrit or the low level of hematuria.
在一家纸浆厂接受广泛健康和环境评估的人群中，识别出一组71名接触氯酚盐的锯木厂工人。将该组与另一组（N = 351）未在使用氯酚盐区域附近工作的人员进行比较。直接接触木材的人员接触程度较高，在该区域工作但不接触木材的人员接触程度较低。接触氯酚盐的人员报告有黄疸或肝脏、肾脏或心脏病史的可能性并无显著增加。此外，血清肌酐、胆红素、谷草转氨酶（GOT）和碱性磷酸酶值与参照组并无差异。三组的血红蛋白水平相似。但接触组的外周血白细胞计数略低，其血细胞比容降低，重度接触组降低显著。尿液分析显示镜下血尿患病率增加，尤其是细胞计数较低时。血细胞比容降低或血尿水平较低尚无明确解释。
