Collaborative Innovation Center of Ecological Civilization, School of Chemical Engineering and Technology, Hainan University, Haikou, China.
Department of Biochemistry, University of Cambridge, Cambridge, UK.
Nat Prod Res. 2024 Sep;38(17):3057-3062. doi: 10.1080/14786419.2023.2214839. Epub 2023 Jun 2.
Chemical examination of an actinomycete strain DSM 4137 derived from a soil sample derived isolate . DSM 3816, yielded a new -asymmetric elaiophylin derivative efomycine U () and a known analogue halichoblelide D (). These structures were unambiguously elucidated on the basis of extensive NMR spectroscopic and mass spectrometric analyses. All compounds isolated were subjected to antimicrobial, cytotoxic and immnosuppressive activities evaluation.
从土壤样本中分离得到的放线菌菌株 DSM 4137 的化学研究。DSM 3816 产生了一种新的不对称的埃洛菲林衍生物 efomycine U () 和一种已知的类似物 halichoblelide D ()。这些结构是基于广泛的 NMR 光谱和质谱分析来明确阐明的。所有分离得到的化合物都进行了抗菌、细胞毒性和免疫抑制活性评估。
