H-2组织相容性复合体的分子生物学
Molecular biology of the H-2 histocompatibility complex.
作者信息
Flavell R A, Allen H, Burkly L C, Sherman D H, Waneck G L, Widera G
出版信息
Science. 1986 Jul 25;233(4762):437-43. doi: 10.1126/science.3726537.
PMID:3726537
Abstract
The H-2 histocompatibility complex of the mouse is a multigene family, some members of which are essential for the immune response to foreign antigens. The structure and organization of these genes have been established by molecular cloning, and their regulation and function is being defined by expression of the cloned genes.
摘要
小鼠的H-2组织相容性复合体是一个多基因家族，其中一些成员对于对外源抗原的免疫反应至关重要。这些基因的结构和组织已通过分子克隆得以确定，其调控和功能正通过克隆基因的表达来界定。
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