Department of First Clinical Medical College, Shandong University of Traditional Chinese Medicine, Jinan, PR China.
Department of Cardiology, Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan, PR China.
Medicine (Baltimore). 2023 Jun 2;102(22):e33926. doi: 10.1097/MD.0000000000033926.
Hypertension is a leading cause of death worldwide. Hypertension is associated with poor sleep quality, which adversely affects physical and mental health, and can increase the incidence rate and mortality of cardiovascular disease, cancer, and depression. This study aimed to investigate the prevalence of the factors related to poor sleep quality in hypertensive patients in Shandong Province, China. This cross-sectional study of adult patients with hypertension from August 2020 to February 2021was conducted in 10 cooperative hospitals in Shandong Province, China. Information was collected in the form of a questionnaire. In this study, Pittsburgh sleep quality index was used to evaluate sleep quality. A multivariate logistic regression model was used to analyze the risk of poor sleep quality. Variables with a P value < 0.05 and a 95% confidence interval (CI) were considered statistically significant. A total of 528 patients with hypertension were included, ranging in age from 31 to 90 years old. The prevalence of poor sleep quality among study participants with hypertension was 319 (60.4%) (95% CI: 0.562-0.646). Female gender (adjusted odds ratios [AOR] = 3.231; 95% CI: 2.194-4.757), stage III blood pressure (AOR = 2.142; 95% CI: 1.108-4.141), mental labor, and labor both physical and mental (AOR = 1.639; 95% CI:1.03-2.611 and AOR = 1.632; 95% CI: 1.030-2.584), unstable marriage (AOR = 3.203; 95% CI: 1.026-9.997) and the very Low-density Lipoprotein (odds ratios = 0.776; 95% CI: 0.649-0.928) were significantly associated with poor sleep quality. This study preliminarily showed that poor sleep quality was a common problem in hypertensive patients, and more than half of the hypertensive patients had poor sleep quality. Poor sleep quality was significantly correlated with gender, hypertension level, occupation, marital status, and the very Low-density Lipoprotein. Considering the negative impact of sleep quality, appropriate strategies should be developed to prevent and treat poor sleep quality in hypertensive patients.
高血压是全球范围内主要的死亡原因之一。高血压与睡眠质量差有关,这会对身心健康产生不利影响,并增加心血管疾病、癌症和抑郁症的发病率和死亡率。本研究旨在调查中国山东省高血压患者中与睡眠质量差相关因素的患病率。这是一项 2020 年 8 月至 2021 年 2 月在中国山东省 10 家合作医院进行的成年高血压患者的横断面研究。以问卷形式收集信息。本研究采用匹兹堡睡眠质量指数评估睡眠质量。采用多变量 logistic 回归模型分析睡眠质量差的风险。具有 P 值<0.05 和 95%置信区间(CI)的变量被认为具有统计学意义。共纳入 528 例高血压患者,年龄 31-90 岁。研究参与者中高血压患者的睡眠质量差患病率为 319 例(60.4%)(95%CI:0.562-0.646)。女性(调整后的优势比[OR] = 3.231;95%CI:2.194-4.757)、三级血压(OR = 2.142;95%CI:1.108-4.141)、脑力劳动和体力劳动(OR = 1.639;95%CI:1.03-2.611 和 OR = 1.632;95%CI:1.030-2.584)、不稳定婚姻(OR = 3.203;95%CI:1.026-9.997)和极低密度脂蛋白(比值比= 0.776;95%CI:0.649-0.928)与睡眠质量差显著相关。本研究初步表明,睡眠质量差是高血压患者的常见问题,超过一半的高血压患者睡眠质量差。睡眠质量差与性别、高血压水平、职业、婚姻状况和极低密度脂蛋白显著相关。考虑到睡眠质量的负面影响,应制定适当的策略来预防和治疗高血压患者的睡眠质量差。