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经椎间孔腰椎体间融合术(TLIF)治疗腰椎退变性疾病后行自然压力引流与负压引流的前瞻性队列研究。

Natural pressure drainage versus negative pressure drainage following transforaminal lumbar interbody fusion (TLIF) for the treatment of lumbar degeneration disease: a prospective cohort study.

机构信息

Department of Orthopedics, The Second Affiliated Hospital of Soochow University, Suzhou, 215006, China.

出版信息

Arch Orthop Trauma Surg. 2023 Oct;143(10):6131-6138. doi: 10.1007/s00402-023-04937-4. Epub 2023 Jun 2.

Abstract

OBJECTIVE

To comprehensively compare the perioperative data and clinical outcomes of natural pressure drainage (NAPD) and negative pressure drainage (NEPD) following transforaminal lumbar interbody fusion (TLIF) for the treatment of lumbar degeneration disease.

METHODS

Between January 2021 and December 2021, 203 patients in our hospital who underwent single- or two-segment TLIF were assigned to the NAPD group (112 patients) or the NEPD group (91 patients) based on different postoperative drainage methods. Between the two groups, comparisons were made regarding the demographics, intraoperative and postoperative data, patient-reported outcomes, and complications.

RESULTS

The NAPD group experienced less overall drainage and fewer postoperative drainage days (157.89 vs. 318.49 ml/249.54 vs. 589.43 ml, 2.00 vs. 2.67 days/2.04 vs. 2.74 days, P < 0.001) than the NEPD group. The NAPD group has a higher rate of overall hidden blood loss (HBL) than the NEPD group (63.98% vs. 51.90%/65.80% vs. 48.11%, P < 0.001); HBL, however, did not significantly differ between the two groups (P > 0.05). In two-segment surgery, the postoperative hemoglobin (HGB) levels were higher in the NAPD group (99.67 vs. 92.69 g/L, P < 0.05), but there was no difference in single-segment surgery (P > 0.05). Regardless of whether single- or two-segment surgery was performed, the NAPD group had a lower HGB level loss (18.81% vs. 21.63%/26.35% vs. 32.08%, P < 0.05). There was no discernible difference between the two groups in the visual analog scale (VAS) scores for symptomatic epidural hematoma, postoperative body temperature, low back and leg pain, or incision infection (P > 0.05).

CONCLUSION

NAPD did not increase postoperative complications but did significantly reduce postoperative drainage volume and the risk of anemia. We show that, when compared to NEPD, NAPD may be a better option for patients following TLIF.

摘要

目的

全面比较经椎间孔腰椎体间融合术(TLIF)治疗腰椎退变性疾病后路采用自然压力引流(NAPD)与负压引流(NEPD)的围手术期数据和临床结果。

方法

2021 年 1 月至 2021 年 12 月,我院 203 例行单节段或双节段 TLIF 的患者,根据术后不同引流方法分为 NAPD 组(112 例)或 NEPD 组(91 例)。对两组患者的一般资料、术中及术后资料、患者报告的结局和并发症进行比较。

结果

与 NEPD 组相比,NAPD 组总引流量更少(157.89 vs. 318.49 ml/249.54 vs. 589.43 ml,P<0.001),术后引流天数更少(2.00 vs. 2.67 天/2.04 vs. 2.74 天,P<0.001)。NAPD 组的总隐匿性失血(HBL)发生率高于 NEPD 组(63.98% vs. 51.90%/65.80% vs. 48.11%,P<0.001),但两组之间 HBL 差异无统计学意义(P>0.05)。在双节段手术中,NAPD 组术后血红蛋白(HGB)水平更高(99.67 vs. 92.69 g/L,P<0.05),但单节段手术中差异无统计学意义(P>0.05)。无论行单节段或双节段手术,NAPD 组 HGB 水平下降幅度均较低(18.81% vs. 21.63%/26.35% vs. 32.08%,P<0.05)。两组在症状性硬膜外血肿、术后体温、腰背腿痛、切口感染的视觉模拟评分(VAS)方面无明显差异(P>0.05)。

结论

NAPD 并未增加术后并发症,但明显减少了术后引流量和贫血风险。我们表明,与 NEPD 相比,NAPD 可能是 TLIF 后患者的更好选择。

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