Tovo P A, Pugliese A, Palomba E, Delpiano A M, Martino S, Incarbone E
Thymus. 1986;8(1-2):91-4.
Four children with measles meningoencephalitis were treated with thymostimulin, a calf thymic extract. All patients were comatose when therapy was started. In all but one a good and sometimes rapid clinical improvement was observed. In the responsive patients no neurological or EEG sequellae were noted over a follow-up period of 1-4 years. The depression of cell-mediated immunity, present in some patients before treatment, normalised at the end of therapy.
4名患麻疹性脑膜炎的儿童接受了胸腺刺激素(一种小牛胸腺提取物)治疗。开始治疗时所有患者均昏迷。除1例患者外,其他患者均出现良好且有时迅速的临床改善。在反应良好的患者中,随访1至4年未发现神经学或脑电图后遗症。部分患者治疗前存在的细胞介导免疫抑制在治疗结束时恢复正常。