• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

子宫内羊水、胎儿和胎盘在军事爆炸中流固耦合分析。

Fluid-structure interaction analysis of amniotic fluid with fetus and placenta inside uterus exposed to military blasts.

机构信息

New York Institute of Technology, College of Osteopathic Medicine, Old Westbury, 11568, New York, USA.

Institute of High Performance Computing, 1 Fusionopolis Way #16-16 Connexis, Singapore, 138632, Singapore.

出版信息

Injury. 2023 Aug;54(8):110843. doi: 10.1016/j.injury.2023.110843. Epub 2023 May 30.

DOI:10.1016/j.injury.2023.110843
PMID:37270348
Abstract

INTRODUCTION

Pregnancy-related trauma is one of the leading causes of morbidity and mortality in pregnant women and fetuses. The fetal response to injury is largely dependent on the timing of fetal presentation and the underlying pathophysiology of the trauma. The optimal management of pregnant patients who have suffered an obstetric emergency depends on clinical assessment and understanding of the placental implantation process, which can be difficult to perform during an emergency. Understanding the mechanisms of traumatic injuries to the fetus is crucial for developing next-generation protective devices.

METHODS

This study aimed to investigate the effect of amniotic fluid on mine blast on the uterus, fetus, and placenta via computational analysis. Finite element models were developed to analyze the effects of explosion forces on the uterus, fetus, and placenta, based on cadaveric data obtained from the literature. This study uses computational fluid-structure interaction simulations to study the effect of external loading on the fetus submerged in amniotic fluid inside of the uterus.

RESULTS

Computational fluid-structure interaction simulations are used to study the effect of external loading on the fetus/placenta submerged in amniotic fluid inside the uterus. Cushioning function of the amniotic fluid on the fetus and placenta is demonstrated. The mechanism of traumatic injuries to the fetus/placenta is shown.

DISCUSSION

The intention of this research is to understand the cushioning function of the amniotic fluid on the fetus. Further, it is important to make use of this knowledge in order to ensure the safety of pregnant women and their fetuses.

摘要

简介

妊娠相关创伤是导致孕妇和胎儿发病率和死亡率的主要原因之一。胎儿对损伤的反应在很大程度上取决于胎儿的表现时机和创伤的潜在病理生理学。对遭受产科急症的孕妇的最佳管理取决于临床评估和对胎盘植入过程的理解,这在紧急情况下很难进行。了解胎儿创伤的机制对于开发下一代保护装置至关重要。

方法

本研究旨在通过计算分析研究羊水对矿山爆炸对子宫、胎儿和胎盘的影响。根据文献中获得的尸体数据,开发有限元模型来分析爆炸力对子宫、胎儿和胎盘的影响。本研究使用计算流固耦合模拟来研究外部加载对子宫内羊水浸泡胎儿的影响。

结果

计算流固耦合模拟用于研究外部加载对子宫内羊水浸泡胎儿/胎盘的影响。证明了羊水对胎儿和胎盘的缓冲功能。显示了胎儿/胎盘创伤的机制。

讨论

本研究的目的是了解羊水对胎儿的缓冲功能。此外,利用这方面的知识对于确保孕妇及其胎儿的安全非常重要。

相似文献

1
Fluid-structure interaction analysis of amniotic fluid with fetus and placenta inside uterus exposed to military blasts.子宫内羊水、胎儿和胎盘在军事爆炸中流固耦合分析。
Injury. 2023 Aug;54(8):110843. doi: 10.1016/j.injury.2023.110843. Epub 2023 May 30.
2
[Contents and distribution of Fe, Cu, Zn, Ni, and Mn in fetuses, amniotic fluid, placenta, and uterus of rats].
Res Exp Med (Berl). 1982;180(3):247-54. doi: 10.1007/BF01852297.
3
Successful use of an artificial placenta-based life support system to treat extremely preterm ovine fetuses compromised by intrauterine inflammation.成功使用基于人工胎盘的生命支持系统治疗因宫内炎症而受损的极早产儿羊胎。
Am J Obstet Gynecol. 2020 Nov;223(5):755.e1-755.e20. doi: 10.1016/j.ajog.2020.04.036. Epub 2020 May 4.
4
Rigid-bar loading on pregnant uterus and development of pregnant abdominal response corridor based on finite element biomechanical model.基于有限元生物力学模型的妊娠子宫刚性杆加载与妊娠腹压反应通道的发展。
Int J Numer Method Biomed Eng. 2020 Jan;36(1):e3284. doi: 10.1002/cnm.3284. Epub 2019 Dec 9.
5
Guidelines for the Management of a Pregnant Trauma Patient.妊娠创伤患者管理指南
J Obstet Gynaecol Can. 2015 Jun;37(6):553-74. doi: 10.1016/s1701-2163(15)30232-2.
6
Development of a Gravid Uterus Model for the Study of Road Accidents Involving Pregnant Women.用于研究涉及孕妇交通事故的妊娠子宫模型的开发。
J Biomech Eng. 2016 Jan;138(1). doi: 10.1115/1.4032055.
7
[Obstetrical ultrasound: can the fetus hear the wave and feel the heat?].[产科超声检查:胎儿能听到声波并感受到热量吗?]
Ultraschall Med. 2012 Jun;33(3):215-7. doi: 10.1055/s-0032-1312759. Epub 2012 Jun 14.
8
Virtual traumatology of pregnant women: the PRegnant car Occupant Model for Impact Simulations (PROMIS).孕妇虚拟创伤学:用于碰撞模拟的妊娠乘客模型(PROMIS)。
J Biomech. 2014 Jan 3;47(1):207-13. doi: 10.1016/j.jbiomech.2013.09.013. Epub 2013 Oct 21.
9
[Fetal causes of the onset of labour. A kybernetic model (author's transl)].[分娩发动的胎儿因素。一个控制论模型(作者译)]
Arch Gynakol. 1977 Jan 27;222(1):15-27. doi: 10.1007/BF00670854.
10
Amniotic fluid interleukin 6 and interleukin 8 are superior predictors of fetal lung injury compared with maternal or fetal plasma cytokines or placental histopathology in a nonhuman primate model.在非人灵长类动物模型中,与母血、脐血细胞因子或胎盘组织病理学比较,羊水白介素 6 和白介素 8 对胎儿肺损伤有更好的预测价值。
Am J Obstet Gynecol. 2021 Jul;225(1):89.e1-89.e16. doi: 10.1016/j.ajog.2020.12.1214. Epub 2021 Jan 4.

引用本文的文献

1
Finite element modeling in obstetrics and gynecology: advances, applications, and challenges.妇产科中的有限元建模:进展、应用与挑战。
Front Med (Lausanne). 2025 Aug 29;12:1606989. doi: 10.3389/fmed.2025.1606989. eCollection 2025.
2
Understanding Traumatic Brain Injuries in Military Personnel: Investigating the Dynamic Interplay of the Cerebrospinal Fluid and Brain During Blasts.了解军事人员的创伤性脑损伤:探究爆炸过程中脑脊液与大脑的动态相互作用。
Cureus. 2023 Oct 13;15(10):e46962. doi: 10.7759/cureus.46962. eCollection 2023 Oct.