Department of Veterinary Medical Imaging, College of Veterinary Medicine, Jeonbuk National University, Iksan 54596, Korea.
Bundang Leaders Animal Medical Center, Seongnam 13636, Korea.
J Vet Sci. 2023 May;24(3):e39. doi: 10.4142/jvs.22328.
A 7-year-old spayed female Shih Tzu dog was presented for evaluation of recurrent hypoglycemia. Serum insulin levels during hypoglycemia were 35.3 μIU/mL. Ultrasonography and computed tomography showed a mesenteric nodule between the kidney and the portal vein, but no pancreatic mass was observed. During surgery, the nodule had neither anatomical adhesions nor vascular connections to the pancreas. Pancreatic inspection and palpation revealed no abnormalities. Hypoglycemia improved after resection of the nodule. Histopathological examination confirmed the nodule to be an islet cell carcinoma. Although extremely rare, ectopic insulinoma should be considered as a possible cause of insulin-induced hypoglycemia in dogs.
一只 7 岁已绝育雌性西施犬因反复发作性低血糖就诊。低血糖时血清胰岛素水平为 35.3 μIU/mL。超声和 CT 显示肠系膜结节位于肾脏和门静脉之间，但未观察到胰腺肿块。术中结节与胰腺无解剖粘连，也无血管联系。胰腺检查和触诊均未见异常。切除结节后低血糖改善。组织病理学检查证实结节为胰岛细胞瘤。尽管极为罕见，但异位胰岛素瘤也应被认为是犬胰岛素诱导性低血糖的可能原因。
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