Abbasi Arezou, Wakeman Kristina M, Pillarisetty Venu G
Department of Surgery, University of Washington, Seattle, WA, USA.
Department of Pathology, University of Washington, Seattle, WA, USA.
Rare Tumors. 2020 Dec 21;12:2036361320982799. doi: 10.1177/2036361320982799. eCollection 2020.
Extra-adrenal paragangliomas are rare tumors arising from the chromaffin cells of the autonomic nervous system. Retroperitoneal paragangliomas may present as a pancreatic mass. We present a case of a 61-year-old woman with an incidentally found pancreatic mass (7.2 × 6.5 cm) in the CT scan. EUS- guided FNA result was compatible with pancreatic neuroendocrine tumor. Patient underwent pancreaticoduodenectomy and histopathologic assessment revealed the mass was an extra-adrenal paraganglioma. Preoperative diagnosis of pancreatic paragangliomas can be challenging due to imaging and histopathologic similarities with pancreatic neuroendocrine tumors.
肾上腺外副神经节瘤是起源于自主神经系统嗜铬细胞的罕见肿瘤。腹膜后副神经节瘤可能表现为胰腺肿块。我们报告一例61岁女性患者，其在CT扫描中偶然发现胰腺肿块（7.2×6.5 cm）。超声内镜引导下细针穿刺活检结果与胰腺神经内分泌肿瘤相符。患者接受了胰十二指肠切除术，组织病理学评估显示该肿块为肾上腺外副神经节瘤。由于胰腺副神经节瘤在影像学和组织病理学上与胰腺神经内分泌肿瘤相似，术前诊断具有挑战性。
