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一名隐形眼镜佩戴者的疱疹性基质性角膜炎非典型表现。

Atypical Presentation of Herpes Stromal Keratitis in a Contact Lens Wearer.

作者信息

Subramaniam Ruknesvary, Sonny Teo Khairy Shamel, Muhammed Julieana

机构信息

Department of Ophthalmology and Visual Sciences, School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian, MYS.

出版信息

Cureus. 2023 May 2;15(5):e38438. doi: 10.7759/cureus.38438. eCollection 2023 May.

Abstract

This article describes the case of a 21-year-old female habitual contact lens wearer who complained of left eye pain, redness, and decreased vision for one week. When a ring-shaped corneal infiltration indicative of an Acanthamoeba infection was discovered, standard anti-amoebic topical therapy with polyhexamethylene biguanide and chlorhexidine was commenced. However, her keratitis worsened. At the same time, corneal scraping revealed no pathogens. An anterior chamber examination revealed a loss of corneal sensation, and a positive herpes simplex virus (HSV) immunoglobulin G serology test indicated HSV keratitis. She was eventually treated with oral anti-viral medication and recovered completely. Her case was unusual, as she had a history of contact lens use, painful corneal ulceration, and the development of Acanthamoeba keratitis-like corneal ring infiltration. This case also reinforces the various manifestations of HSV keratitis, which lead to delayed diagnosis and treatment.

摘要

本文描述了一名21岁习惯性佩戴隐形眼镜的女性病例,她主诉左眼疼痛、发红及视力下降一周。当发现有提示棘阿米巴感染的环形角膜浸润时,开始使用聚六亚甲基双胍和氯己定进行标准的抗阿米巴局部治疗。然而,她的角膜炎恶化了。同时,角膜刮片未发现病原体。前房检查显示角膜感觉丧失,单纯疱疹病毒(HSV)免疫球蛋白G血清学检测呈阳性,提示为HSV角膜炎。她最终接受口服抗病毒药物治疗并完全康复。她的病例不同寻常,因为她有隐形眼镜使用史、疼痛性角膜溃疡以及棘阿米巴角膜炎样角膜环形浸润的发生。该病例还强化了HSV角膜炎的各种表现,这些表现会导致诊断和治疗的延迟。

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