Subramaniam Ruknesvary, Sonny Teo Khairy Shamel, Muhammed Julieana
Department of Ophthalmology and Visual Sciences, School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian, MYS.
Cureus. 2023 May 2;15(5):e38438. doi: 10.7759/cureus.38438. eCollection 2023 May.
This article describes the case of a 21-year-old female habitual contact lens wearer who complained of left eye pain, redness, and decreased vision for one week. When a ring-shaped corneal infiltration indicative of an Acanthamoeba infection was discovered, standard anti-amoebic topical therapy with polyhexamethylene biguanide and chlorhexidine was commenced. However, her keratitis worsened. At the same time, corneal scraping revealed no pathogens. An anterior chamber examination revealed a loss of corneal sensation, and a positive herpes simplex virus (HSV) immunoglobulin G serology test indicated HSV keratitis. She was eventually treated with oral anti-viral medication and recovered completely. Her case was unusual, as she had a history of contact lens use, painful corneal ulceration, and the development of Acanthamoeba keratitis-like corneal ring infiltration. This case also reinforces the various manifestations of HSV keratitis, which lead to delayed diagnosis and treatment.
本文描述了一名21岁习惯性佩戴隐形眼镜的女性病例,她主诉左眼疼痛、发红及视力下降一周。当发现有提示棘阿米巴感染的环形角膜浸润时,开始使用聚六亚甲基双胍和氯己定进行标准的抗阿米巴局部治疗。然而,她的角膜炎恶化了。同时,角膜刮片未发现病原体。前房检查显示角膜感觉丧失,单纯疱疹病毒(HSV)免疫球蛋白G血清学检测呈阳性,提示为HSV角膜炎。她最终接受口服抗病毒药物治疗并完全康复。她的病例不同寻常,因为她有隐形眼镜使用史、疼痛性角膜溃疡以及棘阿米巴角膜炎样角膜环形浸润的发生。该病例还强化了HSV角膜炎的各种表现,这些表现会导致诊断和治疗的延迟。