Căruntu F, Dogaru D, Stefan D, Căruntu V, Angelescu C, Streinu-Cercel A, Colţan G, Petrescu A L, Tarţă D, Bârnaure F
Virologie. 1986 Apr-Jun;37(2):83-7.
The dynamics of the antibody response to influenza viruses A (H1N1), A (H3N2) and B, to parainfluenza viruses 1, 2, 3, to adenoviruses and respiratory syncytial virus was studied in paired serum samples collected from 110 patients hospitalized with acute respiratory infections (ARI) and in 40 patients suffering from other diseases. Rises in serum antibody titers to 1--5 of the above mentioned antigens were detected in many of the patients of both groups. The fact is most likely due to the presence of some epidemiologically and clinically uncharacteristic viral ARI (influenza included); simultaneous or successive infections with influenza virus and different other viruses were very frequent. A greater efficiency of the etiological diagnosis of viral ARI can be achieved only by the association of epidemiological and clinical criteria with serological data, the visualization of viral antigens and virus isolation.
对110例因急性呼吸道感染（ARI）住院的患者以及40例患有其他疾病的患者采集的配对血清样本，研究了其对甲型流感病毒（H1N1）、甲型流感病毒（H3N2）、乙型流感病毒、副流感病毒1、2、3、腺病毒和呼吸道合胞病毒的抗体反应动态。两组中的许多患者血清抗体滴度均升高至上述1 - 5种抗原。这一事实很可能是由于存在一些流行病学和临床特征不明显的病毒性ARI（包括流感）；流感病毒与其他不同病毒同时或相继感染非常频繁。只有将流行病学和临床标准与血清学数据、病毒抗原可视化及病毒分离相结合，才能提高病毒性ARI病因诊断的效率。
